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USP18 Proteins

(Ubiquitin Specific Peptidase 18 (USP18))
The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon, suggesting a function of this protein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15. [provided by RefSeq, Sep 2011].
USP18 Protein (AA 18-268) (His-IF2DI Tag) USP18 Protein (AA 18-268) (His-IF2DI Tag) USP18 Protein (AA 18-268) (His-IF2DI Tag) (ABIN7125590)

USP18 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % by SDS-PAGE gel analyses ELISA, WB

USP18 Protein (AA 273-372) (GST tag) USP18 Protein (AA 273-372) (GST tag) USP18 Protein (AA 273-372) (GST tag) (ABIN1324763)

USP18 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP

USP18 Protein (AA 1-372) (GST tag) USP18 Protein (AA 1-372) (GST tag) USP18 Protein (AA 1-372) (GST tag) (ABIN1324762)

USP18 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP

USP18 Proteins by Grade

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USP18 Proteins by Origin

Find USP18 Proteins for a variety of species such as anti-Human USP18. The species listed below are among those available. Click on a link to go to the corresponding products.

USP18 Proteins by Source

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USP18 Proteins by Protein Type

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USP18 Proteins by Application

Find USP18 Proteins validated for a specific application such as ELISA, WB, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular USP18 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125590
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324763
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324762
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3075216
Quantity 1 mg
Datasheet Datasheet

Aliases for USP18 Proteins

ubiquitin specific peptidase 18 (USP18) Proteins
ubiquitin specific peptidase 18 (Usp18) Proteins
1110058H21Rik Proteins
AW047653 Proteins
bubp43 Proteins
ISG43 Proteins
UBP Proteins
Ubp15 Proteins
UBP43 Proteins
USP18 Proteins
USP41 Proteins
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