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Accepts the ubiquitin-like protein NEDD8 from the UBA3- NAE1 E1 complex and catalyzes its covalent attachment to other proteins. Additionally we are shipping UBE2F Proteins (15) and and many more products for this protein.
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Human Polyclonal UBE2F Primary Antibody for ELISA - ABIN546988
Huang, Ayrault, Hunt, Taherbhoy, Duda, Scott, Borg, Neale, Murray, Roussel, Schulman: E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification. in Molecular cell 2009
Cow (Bovine) Polyclonal UBE2F Primary Antibody for ELISA - ABIN249739
Podust, Brownell, Gladysheva, Luo, Wang, Coggins, Pierce, Lightcap, Chau: A Nedd8 conjugation pathway is essential for proteolytic targeting of p27Kip1 by ubiquitination. in Proceedings of the National Academy of Sciences of the United States of America 2000
By ubiquitylating and degrading NOXA through activating CRL5, UBE2F selectively promotes lung cancer cell survival and could, therefore, serve as a novel cancer target
Distinct preferences of UBC12 and UBE2F peptides for inhibiting different DCNLs, including the oncogenic DCNL1.
Accepts the ubiquitin-like protein NEDD8 from the UBA3- NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5 (By similarity).
, NEDD8-conjugating enzyme UBE2F
, NEDD8 carrier protein UBE2F
, NEDD8 protein ligase UBE2F
, NEDD8-conjugating enzyme 2
, ubiquitin-conjugating enzyme E2 F