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SRC is highly similar to the v-src gene of Rous sarcoma virus. Additionally we are shipping and many more products for this protein.
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Combined targeting of AKT (show AKT1 Antibodies) and SRC resulted in a synergistic efficacy against human pancreatic cancer growth and metastasis.
important roles for c-Src tyrosine kinase (show CSK Antibodies) in phosphorylation and activation of SLC11A1 (show SLC11A1 Antibodies) in macrophages
Our data suggest that targeting Src signaling may be an effective approach to the treatment of ALK-non-small cell lung cancer (NSCLC) with acquired resistance to ALK inhibitors.
Src kinase (show CSK Antibodies) in chemo-naive human primary osteosarcoma cells is differentially activated.
This study demonstrates that simultaneous inhibition of c-Met and Src signaling in MD-MSCs triggers apoptosis and reveals vulnerable pathways that could be exploited to develop NF2 (show NF2 Antibodies) therapies.
Syntenin (show SDCBP Antibodies) mediates SRC function in exosomal cell-to-cell communication.
Endothelial cell-derived matrix promotes the metabolic functional maturation of hepatocyte via integrin-Src signaling.
The expression of Src under the influence of nilotinib, dasatinib, erlotinib, gefitinib and afatinib was studied in HPV-positive head and neck squamous cell carcinomas. Src expression was significantly increased by all tested tyrosine kinase (show TXK Antibodies) inhibitors.
Multivariate Cox (show COX8A Antibodies) regression analysis suggested that PTPRA (show PTPRA Antibodies) expression was an independent prognostic factor in SCC (show CYP11A1 Antibodies) patients. In the cellular models, PTPRA (show PTPRA Antibodies) promotes SCC (show CYP11A1 Antibodies) cell proliferation through modulating Src activation as well as cell cycle progression. In conclusion, higher PTPRA (show PTPRA Antibodies) level was associated with worse prognosis of SCC (show CYP11A1 Antibodies) patients and PTPRA (show PTPRA Antibodies) could promote the cell cycle progression
c-Src/MAPK (show MAPK1 Antibodies)/NF-kB signaling pathway may contribute to the pathogenesis of pre-eclampsia
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
, proto-oncogene tyrosine-protein kinase Src
, protooncogene SRC, Rous sarcoma
, tyrosine kinase pp60c-src
, tyrosine-protein kinase SRC-1