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Transcription factor required for myelination of differentiated oligodendrocytes. Additionally we are shipping Zinc Finger Protein 24 Proteins (7) and Zinc Finger Protein 24 Kits (2) and many more products for this protein.
Showing 10 out of 60 products:
Human Polyclonal ZNF24 Primary Antibody for IHC - ABIN967276
Han, Zhang, Ye, Kan, Gu, He, Shi, Zhou, Fu, Mao, Chen, Yu, Chen: Molecular cloning of six novel Krüppel-like zinc finger genes from hematopoietic cells and identification of a novel transregulatory domain KRNB. in The Journal of biological chemistry 2000
Show all 4 Pubmed References
Cow (Bovine) Polyclonal ZNF24 Primary Antibody for IHC, WB - ABIN2777982
Lv, Zhang, Wang, Meng, Liang, Zhang: Zinc finger protein 191 deficiency attenuates vascular smooth muscle cell proliferation, migration, and intimal hyperplasia after endovascular arterial injury. in Journal of vascular surgery 2014
Show all 2 Pubmed References
Human Polyclonal ZNF24 Primary Antibody for ICC, IF - ABIN4367085
Lopez-Contreras, Ruppen, Nieto-Soler, Murga, Rodriguez-Acebes, Remeseiro, Rodrigo-Perez, Rojas, Mendez, Muñoz, Fernandez-Capetillo: A proteomic characterization of factors enriched at nascent DNA molecules. in Cell reports 2013
ZFP191 played an essential role in aggressive proliferation and migration of vascular smooth muscle cells, which in turn facilitated intimal hyperplasia.
The loss of Zfp191 may suppress systemic inflammation by reducing these cytokine levels during lipopolysaccharide-induced endotoxic shock.
this study demonstrates that ZFP191 is required for the myelinating function of differentiated oligodendrocytes.
These data show that Zfp191 is indispensable for early embryonic development and cell proliferation.
the DNA-binding domain of Zfp191 can specifically bind to the TCAT repeat motif, and there is a cooperative effect among the target DNA's multiple binding sites
Data confirm ZNF191 as an essential factor acting for the promotion of the cell cycle and thus maintenance in the progenitor stage.
miR (show MLXIP Antibodies)-940 promoted gastric cancer progression by directly downregulating ZNF24 expression.
In vivo, knockdown of ZNF24 specifically in microvascular endothelial cells led to significantly decreased formation of functional vascular networks.
results suggest that consecutive ZF1 (show PRMT1 Antibodies)-2 is critical for the regulation of ZNF24 nuclear localization and its transactivation function.
ZNF24 represses VEGF transcription through direct binding to an 11-bp fragment of the VEGF proximal promoter and that it functions as a negative regulator of tumor growth by inhibiting angiogenesis.
ZNF24 may be implicated in transcriptional regulation of genes associated with oncogenesis via interaction with H2A.Z (show H2AFZ Antibodies).
ZNF191 can directly bind to the CTNNB1 (show CTNNB1 Antibodies) promoter and activate the expression of beta-catenin (show CTNNB1 Antibodies) and its downstream target genes such as cyclin D1 (show CCND1 Antibodies) in hepatoma cell lines.
These data suggest that ZNF24 is involved in negative regulation of PDGFR-beta (show PDGFRB Antibodies) and may represent a novel repressor of PDGFR-beta (show PDGFRB Antibodies) transcription.
Overexpression and purification of single zinc finger peptides of ZNF191 were performed.
ZNF191 is a pleiotropic factor that has a role in hematopoiesis, brain development, and tumor growth.
Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically bind to the 5'-TCAT-3' DNA sequence. Has transcription repressor activity in vitro.
hypomyelinated CNS protein
, zinc finger ZF-12
, zinc finger protein 24
, zinc finger protein ZF-12
, lacks zinc finger domain
, retinoic acid suppression protein A
, zinc finger and SCAN domain-containing protein 3
, zinc finger protein 191
, zinc finger protein 24 (KOX 17)
, zinc finger protein KOX17