anti-Zinc Finger Protein 521 (ZNF521) Antibodies

Transcription factor that can both act as an activator or a repressor depending on the context. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ZNF521 307579  
ZNF521 25925 Q96K83
ZNF521 225207 Q6KAS7
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Top anti-Zinc Finger Protein 521 Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: ZNF521 Antibody  - Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm. Immunohistochemistry-Paraffin: ZNF521 Antibody  - Staining of human placenta shows nuclear and cytoplasmic positivity in trophoblastic cells. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated ICC, ELISA, WB 100 μg Log in to see 2 to 3 Days
$375.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-ZNF521 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated EIA, IF, WB   0.1 mg Log in to see 8 to 11 Days
$474.10
Details
Human Rabbit Un-conjugated EIA, IHC (p)   0.1 mg Log in to see 8 to 11 Days
$474.10
Details
Human Rabbit Un-conjugated ELISA, IHC Immunohistochemistry analysis of ZNF521 in human kidney tissue with ZNF521 polyclonal antibody  at 5 ug/mL. 100 μg Log in to see 11 to 12 Days
$355.73
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry-Paraffin: ZNF521 Antibody  - Staining of human placenta shows nuclear positivity in trophoblastic cells. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated ELISA, ICC, WB Immunocytochemical anyalysis of HeLa cells with ZNF521 polyclonal antibody  at 2.5 ug/mL. Western blot analysis of HeLa cell lysate with ZNF521 polyclonal antibody  at 1 ug/mL in (1) the absence and (2) the presence of blocking peptide. 100 μg Log in to see 11 to 12 Days
$355.73
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of ZNF521 in HeLa cell lysate with ZNF521 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide. 0.1 mg Log in to see 2 to 3 Days
$350.00
Details

Top referenced anti-Zinc Finger Protein 521 Antibodies

  1. Human Polyclonal ZNF521 Primary Antibody for ICC, IF - ABIN4367327 : Spina, Filocamo, Iaccino, Scicchitano, Lupia, Chiarella, Mega, Bernaudo, Pelaggi, Mesuraca, Pazzaglia, Semenkow, Bar, Kool, Pfister, Bond, Eberhart, Steinkühler, Morrone: Critical role of zinc finger protein 521 in the control of growth, clonogenicity and tumorigenic potential of medulloblastoma cells. in Oncotarget 2013 (PubMed)

More Antibodies against Zinc Finger Protein 521 Interaction Partners

Human Zinc Finger Protein 521 (ZNF521) interaction partners

  1. Performance metrics were used to select SNPs in stage 1, which were then genotyped to another dataset (stage 2). Four SNPs (CPXM2 (show CPXM2 Antibodies) rs2362967, APOC1 (show APOC1 Antibodies) rs4420638, ZNF521 rs7230380, and rs12965520) were identified for LOAD by both traditional P-values (without correcting for multiple tests) and performance metrics.

  2. IHC based post-Ki67 (show MKI67 Antibodies) levels may have distinct predictive power compared with the naive IHC Ki67 (show MKI67 Antibodies).

  3. knockdown of ZNF521 reduced proliferation in human leukemia cell li (show FUT1 Antibodies)nes possessing MLL-AF9 transloca (show MLL Antibodies)tion (show MLLT3 Antibodies)s

  4. two multi-zinc finger transcription cofactors named ZNF423 (show 104125 Antibodies) and ZNF521 have been characterised as potent inhibitors of EBF1 (show EBF1 Antibodies) and are emerging as potentially relevant contributors to the development of B-cell leukaemias

  5. Data show that zinc finger protein 521 (ZNF521) can function as a repressor of osteoblastic differentiation of bone marrow mesenchymal stem cells (bmMSCs).

  6. Newly discovered ZNF521-molecular partners of potentially relevant functional role, such as ZNF423 (show 104125 Antibodies), Spt16 (show SUPT16H Antibodies), Spt5 (show SUPT5H Antibodies), were discovered and validated by Western blotting.

  7. Data strongly support the notion that ZNF521, through the recruitment of the NuRD complex, contributes to the clonogenic growth, migration and tumorigenicity of medulloblastoma cells.

  8. Data show that ZNF521 can antagonize B-cell development and support the notion that it may contribute to conserve the multipotency of primitive lympho-myeloid progenitors by preventing or delaying their EBF1 (show EBF1 Antibodies)-driven commitment toward the B-cell lineage.

  9. Zinc finger protein 521, a new player in bone formation.

  10. EHZF is likely to play a relevant role in the control of human hematopoiesis and might be implicated in the development of hematopoietic malignancies.

Mouse (Murine) Zinc Finger Protein 521 (ZNF521) interaction partners

  1. The pre-B-cell receptor (pre-BCR (show BCR Antibodies)) signaling molecules BLNK (show BLNK Antibodies), BTK (show BTK Antibodies) and BANK1 (show BANK1 Antibodies) were positively regulated by the ZFP521 gene, leading to enhancement of the pre-BCR (show BCR Antibodies) signaling pathway.

  2. these results identify ZNF521/ZFP521 as a critical regulator of HSC (show FUT1 Antibodies) function, which facilitates MLL (show MLL Antibodies)-AF9 (show MLLT3 Antibodies)-mediated leukemic disease in mice.

  3. links between dysregulated Zfp521 and B-cell survival

  4. Here we demonstrate that the transcription factors SPI1 (show SPI1 Antibodies) (PU.1) and HOXC13 synergistically regulate Zfp521 expression, and identify the regions of the Zfp521 promoter required for this transcriptional activity. We also show that SPI1 (show SPI1 Antibodies) and HOXC13 activate Zfp521 in a dose-dependent manner.

  5. Data suggest a facilitated approach for establishing human neural stem cells (NSCs) through zinc finger protein 521 (Zfp521)-driven conversion of fibroblasts.

  6. it is concluding that an enhanced expression of Fndc5 (show FNDC5 Antibodies) in neural progenitor cells is stimulated by Zfp521 overexpression in these cells

  7. Data show that zinc finger protein 521 (ZNF521) overexpression repressed osteoblastic differentiation of C3H10T1/2 cells.

  8. Runx1 (show RUNX1 Antibodies)-dependent transcription factor gene Zfp521 is expressed in, and required for establishing molecular features that define, mechanoreceptors.

  9. the data suggest that Zfp521 is a cell fate switch critical for BMP-induced osteoblast commitment and identify Zfp521 as the intrinsic repressor of Zfp423 and hence of adipocyte commitment during BMP-induced mesenchymal precursor differentiation.

  10. the interplay between Zfp521 and Ebf1 (show EBF1 Antibodies) is identified as a novel rheostat for bone homeostasis.

Zinc Finger Protein 521 (ZNF521) Antigen Profile

Protein Summary

Transcription factor that can both act as an activator or a repressor depending on the context. Involved in BMP signaling and in the regulation of the immature compartment of the hematopoietic system. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved specification of B-cell lineage\; this interaction preventing EBF1 to bind DNA and activate target genes.

Gene names and symbols associated with ZNF521

  • zinc finger protein 521 (Zfp521) antibody
  • zinc finger protein 521 (ZNF521) antibody
  • zinc finger protein 521 S homeolog (znf521.S) antibody
  • B930086A16Rik antibody
  • EHZF antibody
  • Evi3 antibody
  • Znf521 antibody

Protein level used designations for ZNF521

LYST-interacting protein 3 , early hematopoietic zinc finger protein , ecotropic viral integration site 3 protein

GENE ID SPECIES
307579 Rattus norvegicus
421083 Gallus gallus
490511 Canis lupus familiaris
538792 Bos taurus
25925 Homo sapiens
225207 Mus musculus
414550 Xenopus laevis
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