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May be involved in transcriptional regulation.. Additionally we are shipping Zinc Finger Protein 671 Antibodies (19) and and many more products for this protein.
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Data show that mRNA and protein expression of ZNF671 are down-regulated in nasopharyngeal cancer (NPC (show NPC1 Proteins)) tissues and cell lines. Its downregulation promotes NPC (show NPC1 Proteins) cell proliferation and tumorigenicity by facilitating cell cycle progression. These results suggest that ZNF671 is a potential tumor suppressor which epigenetically silenced by promoter methylation in NPC (show NPC1 Proteins).
In particular, methylation levels of ITGA4 (show ITGA4 Proteins), RERG (show RERG Proteins), and ZNF671 could distinguish Nasopharyngeal carcinoma (NPC (show NPC1 Proteins)) patients from non-cancer nasopharyngeal epithelium (NNE) subjects. We identified the DNA methylation (show HELLS Proteins) rates of previously unidentified NPC (show NPC1 Proteins) candidate genes.
Data show that ZNF671, an epigenetically silenced tumor suppressor, represents a potential predictor for urothelial carcinoma (UC) relapse and non-invasive biomarker that could assist in UC clinical decision-making.
May be involved in transcriptional regulation.
zinc finger protein 671
, zinc finger protein 671-like