anti-Zinc Finger and BTB Domain Containing 33 (ZBTB33) Antibodies

ZBTB33 encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. Additionally we are shipping ZBTB33 Proteins (4) and ZBTB33 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ZBTB33 10009 Q86T24
ZBTB33 56805 Q8BN78
ZBTB33 501506  
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Top anti-ZBTB33 Antibodies at

Showing 10 out of 34 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-ZBTB33 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HepG2 cell lysate WB Suggested Anti-ZBTB33 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: Kaiso Antibody [NBP1-87866] - Staining of human breast shows moderate nuclear positivity in glandular cells. Immunocytochemistry/Immunofluorescence: Kaiso Antibody [NBP1-87866] Staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli, plasma membrane & cytoplasm. 0.1 mL Log in to see 10 to 13 Days
Human Mouse Un-conjugated WB Western Blot analysis of ZBTB33 expression in transfected 293T cell line by ZBTB33 monoclonal antibody (M01), clone 2B2. Lane 1: ZBTB33 transfected lysate(74.6 KDa). Lane 2: Non-transfected lysate. Western blot analysis of ZBTB33 over-expressed 293 cell line, cotransfected with ZBTB33 Validated Chimera RNAi used as specificity and loading control. 0.05 mg Log in to see 8 to 11 Days
Cow Rabbit Un-conjugated IHC (p), WB Human Small Intestine, Vessel (formalin-fixed, paraffin-embedded) stained with ZBTB33 antibody ABIN213733 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
Mouse Mouse Un-conjugated WB Kaiso mAb (Clone 6F1D) tested by Western blot. Nuclear extract of CSML0 cells (20 µg) was probed with Kaiso mAb (Clone 6F1D) (1 µg/ml dilution). 200 μg Log in to see 1 to 2 Days
Human Rabbit Un-conjugated WB Western Blot: Kaiso Antibody [NBP1-80316] - HepG2 cell lysate, concentration 0.2-1 ug/ml. 100 μL Log in to see 8 to 11 Days
Chicken Mouse Un-conjugated IP, IHC, WB   200 μg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated WB ZBTB33 antibody used at 0.2-1 ug/ml to detect target protein. 50 μg Log in to see 6 to 8 Days
Dog Mouse Un-conjugated MA, WB   0.1 mg Log in to see 7 to 9 Days

ZBTB33 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , ,
, ,
Mouse (Murine) ,
Rat (Rattus) ,

Top referenced anti-ZBTB33 Antibodies

  1. Human Polyclonal ZBTB33 Primary Antibody for ICC, IF - ABIN4328014 : Zhang, Gallup, Zlock, Feeling Chen, Finkbeiner, McNamara: Cigarette Smoke Mediates Nuclear to Cytoplasmic Trafficking of Transcriptional Inhibitor Kaiso through MUC1 and P120-Catenin. in The American journal of pathology 2016 (PubMed)

More Antibodies against ZBTB33 Interaction Partners

Xenopus laevis Zinc Finger and BTB Domain Containing 33 (ZBTB33) interaction partners

  1. Dyrk1A (show DYRK1A Antibodies) positively and selectively modulates p120-catenin (show CTNND1 Antibodies) protein levels, thus having an impact on p120-catenin (show CTNND1 Antibodies) and Kaiso (and canonical Wnt (show WNT2 Antibodies)) gene targets such as siamois and wnt11.

  2. xKaiso plays an essential role as a global repressor of methylated genes during early vertebrate development.

  3. propose that mutual inhibition by Kaiso/TCF3 (show TCF3 Antibodies) of their DNA-binding functions may be important in developmental or cancer contexts and acts as a regulatory node that integrates epigenetic and Wnt (show WNT2 Antibodies) signalling pathways

  4. The major phenotypic defects associated with xKaiso depletion are premature transcription activation before the mid-blastula transition and concomitant activation of a p53 (show TP53 Antibodies)-dependent cell-death pathway

  5. Kaiso is a bimodal modulator for Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling.

Human Zinc Finger and BTB Domain Containing 33 (ZBTB33) interaction partners

  1. A role for Kaiso in the proliferation.

  2. Suggest a role for Kaiso in the progression of pancreatic ductal adenocarcinomas, involving the epithelial mesenchymal transformation markers, E-cadherin (show CDH1 Antibodies) and Zeb1 (show ZEB1 Antibodies).

  3. a novel mechanism by which ZBTB33 mediates the cyclin D1 (show CCND1 Antibodies)/cyclin E1 (show CCNE1 Antibodies)/RB1 (show RB1 Antibodies)/E2F (show E2F1 Antibodies) pathway, controlling passage through the G1 restriction point and accelerating cancer cell proliferation.

  4. GR is a putative target gene of Kaiso.

  5. Kaiso high expression correlated with invasion of prostate cancer.

  6. Results show that Kaiso binding to unmethylated Kaiso binding site in the human ICR1 is necessary for ICR1 methylation maintenance and affects transcription rates of the lncRNA H19 (show NCKAP1 Antibodies).

  7. Kaiso modulates HIF1A (show HIF1A Antibodies) gene expression by binding to the methylated HIF1A (show HIF1A Antibodies) promoter in a region proximal to the autoregulatory HIF-1 (show HIF1A Antibodies) binding site, primarily during hypoxia.

  8. NF-kappaB (show NFKB1 Antibodies) response element, located close to the p53RE#1, mediates APAF1 (show APAF1 Antibodies) transcriptional repression by affecting interaction between KAISO and p53 (show TP53 Antibodies)

  9. KAISO is a regulator of p53 (show TP53 Antibodies)-mediated transcription of CDKN1A and apoptotic genes

  10. Data indicate that Kaiso protein participates in the regulation of beta-catenin (show CTNNB1 Antibodies) mRNA expression by interacting with p120-catenin (show CTNND1 Antibodies) in the lung cancer cell lines.

Mouse (Murine) Zinc Finger and BTB Domain Containing 33 (ZBTB33) interaction partners

  1. We also demonstrate that Kaiso inhibits Znf131 (show ZNF131 Antibodies) expression, raising the possibility that Kaiso and Znf131 (show ZNF131 Antibodies) act to fine-tune target gene expression. Together, our findings implicate Znf131 (show ZNF131 Antibodies) as a co-regulator of Kaiso-mediated biological processes.

  2. Kaiso and Sox10 (show SOX10 Antibodies) sequentially interact with Tcf7l2 (show TCF7L2 Antibodies) to coordinate the maturation of oligodendrocyte.

  3. Study revealed the involvement of the Zbtb33 gene and, probably, the Kaiso protein in the regulation of locomotion and brain morphology in mice

  4. a mechanistic link between E-cadherin (show CDH1 Antibodies) loss and subsequent control of Rho-driven anoikis resistance through p120 (show CTNND1 Antibodies)- and Kaiso-dependent expression of Wnt11 (show WNT11 Antibodies), is reported.

  5. S100A3 (show S100A3 Antibodies) is a new target gene of Kaiso in mouse skin

  6. ZBTB33 expression may elicit intestinal inflammation by antagonizing p120ctn (show CTNND1 Antibodies) function.

  7. derepressed Bcl6 (show BCL6 Antibodies) expression may be responsible for increases in germinal centers cell proliferation and splenomegaly of Kaiso knockout mice.

  8. KAISO, similar to SMRT, accelerates the cell cycle and increases fat accumulation upon knockdown, identifying KAISO as an adipogenic repressor that likely modulates the mitotic clonal expansion phase of this process.

  9. Znf131 (show ZNF131 Antibodies) is a transcriptional activator, a less common function of POZ-ZF proteins, that is negatively regulated by its heterodimerization partner Kaiso.

  10. These results provide the first experimental evidence that rapsyn (show RAPSN Antibodies) is a direct sequence-specific target of Kaiso and delta-catenin (show CTNND2 Antibodies).

ZBTB33 Antigen Profile

Protein Summary

This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-alpha2 (also known as karyopherin alpha2 or RAG cohort 1), which may mediate nuclear import of this protein. Alternatively spliced transcript variants encoding the same protein have been identified.

Gene names and symbols associated with ZBTB33

  • zinc finger and BTB domain containing 33 S homeolog (zbtb33.S) antibody
  • zinc finger and BTB domain containing 33 (ZBTB33) antibody
  • zinc finger and BTB domain containing 33 (Zbtb33) antibody
  • AW260253 antibody
  • E130014G12Rik antibody
  • Kaiso antibody
  • RGD1566309 antibody
  • Znf-kaiso antibody
  • ZNF348 antibody

Protein level used designations for ZBTB33

DNA-methylation dependent transcriptional repressor Kaiso-like protein , transcriptional regulator Kaiso , xKaiso , zinc finger and BTB domain-containing protein 33 , WUGSC:H_DJ525N14.1 , kaiso transcription factor , zinc finger transcription factor Kaiso , Kaiso

398248 Xenopus laevis
10009 Homo sapiens
100685062 Canis lupus familiaris
784871 Bos taurus
56805 Mus musculus
501506 Rattus norvegicus
422367 Gallus gallus
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