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ALPK1 encodes an alpha kinase. Additionally we are shipping ALPK1 Proteins (4) and and many more products for this protein.
Showing 10 out of 29 products:
Human Polyclonal ALPK1 Primary Antibody for ICC, IF - ABIN4280191
Fagerberg, Oksvold, Skogs, Algenäs, Lundberg, Pontén, Sivertsson, Odeberg, Klevebring, Kampf, Asplund, Sjöstedt, Al-Khalili Szigyarto, Edqvist, Olsson, Rydberg, Hudson, Ottosson Takanen, Berling et al.: Contribution of antibody-based protein profiling to the human Chromosome-centric Proteome Project (C-HPP). ... in Journal of proteome research 2013
Show all 2 Pubmed References
Combined exposure to the four high-risk genotypes of ALPK1 and the uric-acid-related loci of ABCG2, SLC2A9 (show SLC2A9 Antibodies), and SLC22A12 (show SLC22A12 Antibodies) was associated with an increased gout risk and a high PPV (show PPP6C Antibodies) for gout.
In lung and colorectal cancer tissues, the ALPK1 RNA level of the normal part was higher than that of the tumor part. these findings suggested that ALPK1 might play a vital role in cancer development.
ALPK1 is a kinase that participates in the regulation of Golgi-derived TNF-alpha (show TNF Antibodies) trafficking through myosin IIA phosphorylation in the inflammation of gout.
ERN1 (show ERN1 Antibodies) and ALPK1 inhibit differentiation of bi-potential tumor-initiating cells in human triple negative breast cancer.
these results clearly show that ALPK1 is a master regulator of innate immunity against both invasive and extracellular gram-negative bacteria.
findings suggest that among genes in a gout-susceptibility locus, not ALPK1 but ABCG2 could be important as a gout-susceptible gene
single nucleotide polymorphisms in the alpha-protein kinase 1 (ALPK1) gene are associated with gout in Han Chinese Taiwanese.
ALPK1 may be a susceptibility gene for chronic kidney disease in such individuals with diabetes mellitus.
ALPK1 is a gout-susceptible gene involved in Monosodium urate monohydrate-induced inflammatory responses and may contribute to the development of gout by enhancing the inflammatory responses via the MAP kinase (show MAPK1 Antibodies) pathway
Transposon-inserted Alpk1 homozygous mutant mice display severe defects in motor coordination in a series of behavioral analyses.
data suggests that the balance between ALPK1 and testosterone plays a critical role in the testosterone-mediated inhibition of proinflammatory cytokines
This gene encodes an alpha kinase. Mice which were homozygous for disrupted copies of this gene exhibited coordination defects (PMID: 21208416). Multiple transcript variants encoding different isoforms have been found for this gene.
, alpha-protein kinase 1-like
, alpha-protein kinase 1
, chromosome 4 kinase
, lymphocyte alpha-kinase
, lymphocyte alpha-protein kinase