serum/glucocorticoid Regulated Kinase Family, Member 3 Proteins (SGK3)

SGK3 is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. Additionally we are shipping serum/glucocorticoid Regulated Kinase Family, Member 3 Antibodies (126) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SGK3 23678 Q96BR1
SGK3 170755 Q9ERE3
SGK3 171498  
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Top serum/glucocorticoid Regulated Kinase Family, Member 3 Proteins at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,797.11
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,797.11
Details
Baculovirus infected Insect Cells Human GST tag,His tag 50 μg Log in to see 20 to 21 Days
$272.80
Details
Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$704.00
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
Details
Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$338.33
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Log in to see Available
$284.90
Details
Insect Cells Human GST tag 100 μg Log in to see 11 to 12 Days
$1,502.67
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,406.33
Details

SGK3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
, , ,
Mouse (Murine) ,
,
Rat (Rattus) ,

More Proteins for serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3) Interaction Partners

Human serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3) interaction partners

  1. Hence, we concluded that miR1443p, which is frequently downregulated in hepatocellular carcinoma (HCC (show FAM126A Proteins)) can inhibit proliferation, migration and repress angiogenesis by regulating SGK3 activation with PI3K (show PIK3CA Proteins) independent signal pathway, and acts as a prognostic factor for HCC (show FAM126A Proteins) patients.

  2. SGK3 a kinase transcriptionally regulated by estrogen receptor alpha (ERalpha (show ESR1 Proteins)) in breast cancer, sustains ERalpha (show ESR1 Proteins) signaling and drives the acquired aromatase (show CYP19A1 Proteins) inhibitors resistance by protecting against endoplasmic reticulum (EnR (show LARGE Proteins)) stress-induced ERalpha (show ESR1 Proteins) downregulation and cell death through preserving SERCA2b (show ATP2A2 Proteins) function.

  3. High SGK3 expression is associated with epithelial-mesenchymal transition in hepatocellular carcinoma.

  4. These findings highlight the importance of the hVps34 (show PIK3C3 Proteins)-SGK3 pathway in counteracting inhibition of PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins) signalling.

  5. Data show that activation of serum- and glucocorticoid-regulated kinase 3 (SGK3) plays an important role in inositol polyphosphate 4-phosphatase type II (INPP4B (show INPP4B Proteins))-mediated melanoma cell proliferation.

  6. It is unlikely that SGK3 plays a significant role for oncogenic signalling in multiple myeloma.

  7. SGK3 is a key mediator of PDK1 (show PDK1 Proteins) activity in melanoma.

  8. VPS34 (show PIK3C3 Proteins)-IN1 will provide a useful tool to decipher the kinase-dependent functions of Vps34 (show PIK3C3 Proteins), with acute changes in SGK3 phosphorylation and subcellular localization being new biomarkers of Vps34 (show PIK3C3 Proteins) activity

  9. Breast cancers harboring oncogenic PIK3CA (show PIK3CA Proteins) activate SGK3 signaling while suppressing Akt (show AKT1 Proteins), indicative of oncogenic functions for both INPP4B (show INPP4B Proteins) and SGK3 in these tumors.

  10. SGK3 is an androgen receptor (AR (show AR Proteins)) target and induces cell proliferation through the AR-SGK3-p70S6K (show RPS6KB1 Proteins)-cyclin D1 (show CCND1 Proteins) pathway in prostate cancer cells.

Mouse (Murine) serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3) interaction partners

  1. SGK1 (show SGK1 Proteins) and SGK3 are expressed in multiple microglial cell lines. SGK1 (show SGK1 Proteins) and SGK3 may play an important role in regulating microglial viability and inflammatory responses.

  2. SGK3 is a positive regulator of KCNA5 (show KCNA5 Proteins), which is at least partially effective by abrogating the effect of Nedd4-2 (show NEDD4L Proteins).

  3. SGK3 contributes to the regulation of store-operated calcium entry into and migration of dendritic cells.

  4. SGK3 plays a previously unappreciated role in glucose homeostasis, likely through direct effects within pancreatic beta-cells, to stimulate proliferation and insulin (show INS Proteins) release

  5. The study identifies SGK3 as a novel endosomal kinase that acutely regulates Na(+)/H(+) exchanger 3 (NHE3 (show SLC9A3 Proteins)) in a PI3K-dependent mechanism.

  6. SGK3 has a subtle but significant role in the regulation of renal tubular phosphate transport and bone density.

  7. Data suggest that SGK3 is critical for proper mast cell function.

  8. SGK3 plays an important role in postnatal hair follicle development as illustrated by SGK3 knockout mice. The hair defect is linked to reduced proliferation and reduced nuclear accumulation of beta catenin (show CTNNB1 Proteins) in hair bulb keratinocytes.

  9. SGK3 is differentially regulated in hippocampus after contextual fear conditioning & reactivation of the context-shock memory. Consolidation changes are recapitulated during reconsolidation. Retrieval-induced transcription depends on memory remoteness.

  10. SGK3, and to a lesser extent SGK2 (show SGK2 Proteins), but not SGK1 (show SGK1 Proteins), increase glutamate (show GRIN1 Proteins)-induced currents by increasing the abundance of GluR1 (show GRIA1 Proteins) protein in the cell membrane

serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3) Protein Profile

Protein Summary

This gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with SGK3

  • serum/glucocorticoid regulated kinase family member 3 (SGK3)
  • serum/glucocorticoid regulated kinase 3 (Sgk3)
  • serum/glucocorticoid regulated kinase family, member 3 (Sgk3)
  • serine/threonine-protein kinase Sgk3 (LOC464217)
  • serum/glucocorticoid regulated kinase family, member 3 (sgk3)
  • serine/threonine-protein kinase Sgk3 (LOC100231693)
  • serine/threonine-protein kinase Sgk3 (LOC100343709)
  • serum/glucocorticoid regulated kinase family, member 3 (SGK3)
  • serine/threonine-protein kinase Sgk3 (LOC100052030)
  • serine/threonine-protein kinase Sgk3 (LOC100521447)
  • 2510015P22Rik protein
  • A330005P07Rik protein
  • Cisk protein
  • fy protein
  • fz protein
  • SGK2 protein
  • Sgkl protein
  • zgc:162253 protein

Protein level used designations for SGK3

cytokine-independent survival kinase , serine/threonine-protein kinase Sgk3 , serine/threonine protein kinase CISK , serum/glucocorticoid-regulated kinase 3 , serum/glucocorticoid regulated kinase 3 , serum glucocorticoid regulated kinase 3

GENE ID SPECIES
23678 Homo sapiens
170755 Mus musculus
171498 Rattus norvegicus
420167 Gallus gallus
464217 Pan troglodytes
564523 Danio rerio
100231693 Taeniopygia guttata
100343709 Oryctolagus cuniculus
486981 Canis lupus familiaris
100052030 Equus caballus
100521447 Sus scrofa
504480 Bos taurus
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