HsTx1
-
- Target
- HsTx1 (HSTX1) (Hybrid Sterility, X Chromosome 1 (HSTX1))
- Application
- Blocking Reagent (BR)
- Purpose
- HsTx1 is a Kv1.3 channel blocker
- Sequence
- Ala-Ser-Cys3-Arg-Thr-Pro-Lys-Asp-Cys9-Ala-Asp-Pro-Cys13-Arg-Lys-Glu-Thr-Gly-Cys19-Pro-Tyr-Gly-Lys-Cys24-Met-Asn-Arg-Lys-Cys29-Lys-Cys31-Asn-Arg-Cys34-NH2Disulfide bonds between Cys3-Cys24, Cys9-Cys29,Cys13-Cys31 and Cys19-Cys34
-
- Restrictions
- For Research Use only
-
-
- Target
- HsTx1 (HSTX1) (Hybrid Sterility, X Chromosome 1 (HSTX1))
- Alternative Name
- HsTx1
- Background
- HsTx1 is a member of the a-KTx6 family of toxins active on voltage-gated K+ v1.3 channels (Kd close to 10 pM). It is also very active on Kv1.2 channels (Kd around 7 nM). It is however inactive on apamin-sensitive SK channels. It is one of the most potent toxins active on K channels.
- Molecular Weight
- 3819.87 Da
-
You are here:
