anti-Mouse (Murine) CYP11B2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended CYP11B2 Antibody (supplied by: Log in to see )

Antigen
Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2) Antibodies
  • ALDOS
  • CPN2
  • CYP11B
  • CYP11BL
  • CYPXIB2
  • P-450C18
  • P450C18
  • P450aldo
  • Cpn2
  • Cyp11b
  • Cyp11b-2
  • Cp45as
  • Cyp11b3
  • RNCP45AS
  • cytochrome P450 family 11 subfamily B member 2
  • cytochrome P450, family 11, subfamily b, polypeptide 2
  • aldosterone synthase
  • cytochrome P450, family 11, subfamily B, polypeptide 2
  • cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2
  • CYP11B2
  • Cyp11b2
Epitope
AA 127-155, Middle Region
8
8
7
6
4
2
1
1
1
Reactivity
Human, Mouse (Murine)
49
29
19
1
Host
Rabbit
50
2
Clonality
Polyclonal
Conjugate
This CYP11B2 antibody is un-conjugated
4
4
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
34
25
19
15
13
6
3
2
1
1
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Catalog No. ABIN951773
$ 484.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
10 ABIN5535338 FACS IHC (p) WB Rabbit Ig Fraction AA 120-147 Log in to see Polyclonal 0
1 ABIN1711272 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal 0
1 ABIN1700255 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal 0
1 ABIN1713757 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2) Antibodies
Epitope AA 127-155, Middle Region
(8), (8), (7), (6), (4), (2), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(49), (29), (19), (1)
Host Rabbit
(50), (2)
Clonality
Polyclonal
Conjugate This CYP11B2 antibody is un-conjugated
(4), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(34), (25), (19), (15), (13), (6), (3), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-CYP11B2 Antibody

Target Details CYP11B2 Application Details Handling References for anti-CYP11B2 antibody (ABIN951773) Images
Specificity This antibody recognizes Human and Mouse CYP11B2 (Center).
Purification Affinity Chromatography on Protein A
Immunogen KLH conjugated synthetic peptide between 127-155 amino acids from the Central region of Human CYP11B2. Genename: CYP11B2
Isotype Ig Fraction
Plasmids, Primers & others

Target Details CYP11B2

Product Details anti-CYP11B2 Antibody Application Details Handling References for anti-CYP11B2 antibody (ABIN951773) Images back to top
Antigen
Alternative Name CYP11B2 (CYP11B2 Antibody Abstract)
Background This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.Synonyms: ALDOS, Aldosterone synthase, Aldosterone-synthesizing enzyme, CYPXIB2, Cytochrome P450 11B2, P-450Aldo, P-450C18, Steroid 18-hydroxylase
Molecular Weight 57560 Da
Gene ID 1585
NCBI Accession NP_000489
Pathways ACE Inhibitor Pathway, Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process, Feeding Behaviour

Application Details

Product Details anti-CYP11B2 Antibody Target Details CYP11B2 Handling References for anti-CYP11B2 antibody (ABIN951773) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CYP11B2 Antibody Target Details CYP11B2 Application Details References for anti-CYP11B2 antibody (ABIN951773) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-CYP11B2 antibody (ABIN951773)

Product Details anti-CYP11B2 Antibody Target Details CYP11B2 Application Details Handling Images back to top
Background publications

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010

Images

Product Details anti-CYP11B2 Antibody Target Details CYP11B2 Application Details Handling References for anti-CYP11B2 antibody (ABIN951773) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2) (AA 127-155), (Middle Region) antibody (ABIN951773) Flow cytometric analysis of CEM cells using CYP11B2 Antibody (Center) Cat.-No AP51163...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2) (AA 127-155), (Middle Region) antibody (ABIN951773) Formalin fixed, paraffin embedded mouse kidney tissue followed stained with CYP11B2 A...
Western Blotting (WB) image for anti-Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2) (AA 127-155), (Middle Region) antibody (ABIN951773) Western blot analysis of CYP11B2 Antibody (Center) in CEM cell line lysates (35ug/lan...