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CD86 Proteins

(CD86)
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011].
CD86 Protein (CD86) (AA 26-247) (Fc Tag) CD86 Protein (CD86) (AA 26-247) (Fc Tag) CD86 Protein (CD86) (AA 26-247) (Fc Tag) (ABIN7273897)

CD86 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

CD86 Protein (CD86) (His-Avi Tag) CD86 Protein (CD86) (His-Avi Tag) CD86 Protein (CD86) (His-Avi Tag) (ABIN7273898)

CD86 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC

CD86 Protein (CD86) (AA 26-240) (His tag) CD86 Protein (CD86) (AA 26-240) (His tag) CD86 Protein (CD86) (AA 26-240) (His tag) (ABIN7273896)

CD86 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

CD86 Proteins by Grade

Find CD86 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

CD86 Proteins by Origin

Find CD86 Proteins for a variety of species such as anti-Human CD86, anti-Mouse CD86, anti-Cynomolgus CD86. The species listed below are among those available. Click on a link to go to the corresponding products.

CD86 Proteins by Source

Here you will find CD86 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

CD86 Proteins by Protein Type

Here you can find CD86 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

CD86 Proteins by Application

Find CD86 Proteins validated for a specific application such as WB, ELISA, SDS, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

CD86 Proteins by Biological Activity

Find CD86 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular CD86 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7273897
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7273898
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7273896
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus, Rhesus Monkey
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN2180853
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (3)
Cat. No. ABIN2180621
Quantity 200 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7273899
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293T Cells
Validations
  • (2)
Cat. No. ABIN1348720
Quantity 25 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN2870717
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN2180618
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN3137664
Quantity 200 μg
Datasheet Datasheet
Reactivity Rhesus Monkey
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320996
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320769
Quantity 50 μg
Datasheet Datasheet
Reactivity Rabbit
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320993
Quantity 50 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320949
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122216
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our CD86 Proteins

Li, Li, Chu, Wang: "A functional antibody cross-reactive to both human and murine cytotoxic T-lymphocyte-associated protein 4 via binding to an N-glycosylation epitope." in: mAbs, Vol. 12, Issue 1, pp. 1725365, (2020) (PubMed).

Zhao, Lee, Lin, Gassen, Xu, Huang, Xiao, Bonorino, Lu, Bui, Hui: "PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways." in: Immunity, Vol. 51, Issue 6, pp. 1059-1073.e9, (2019) (PubMed).

Gmyrek, Pingel, Choi, Green: "Functional analysis of acquired CD28 mutations identified in cutaneous T cell lymphoma." in: Cellular immunology, Vol. 319, pp. 28-34, (2017) (PubMed).

Aliases for CD86 Proteins

CD86 molecule (CD86) Proteins
CD86 antigen (Cd86) Proteins
CD86 molecule (Cd86) Proteins
integrin subunit alpha 2b (Itga2b) Proteins
B7 Proteins
B7-2 Proteins
B7.2 Proteins
B70 Proteins
Cd28l2 Proteins
CD28LG2 Proteins
CLS1 Proteins
ETC-1 Proteins
LAB72 Proteins
Ly-58 Proteins
Ly58 Proteins
MB7 Proteins
MB7-2 Proteins
TS/A-2 Proteins
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