GM-CSF antibody

Details for Product No. ABIN100060
Antigen
Reactivity
Human
115
35
19
19
15
3
3
1
1
Host
Rabbit
83
40
34
5
1
Clonality
Polyclonal
Conjugate
Un-conjugated
20
4
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Neutralization (Neut), Radioimmunoassay (RIA), ELISA, Western Blotting (WB)
110
64
44
33
25
24
22
21
14
11
9
7
4
3
3
2
2
2
1
1
Options
Immunogen This whole rabbit serum was prepared by repeated immunizations with full length recombinant human GM-CSF.
Immunogentype:Recombinant
Characteristics Concentration Definition: by Refractometry
Purification Antiserum
Sterility Sterile filtered
Antigen
Background Granulocyte Macrophage Colony Stimulating Factor (also known as GM-CSF, Colony-stimulating factor; CSF, sargramostim and molgramostin) is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. Granulocyte Macrophage-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages. GM-CSF receptors show significant homologies with other receptors for hematopoietic growth factors, including IL2-beta, IL-3, IL-6, IL-7, EPO and the Prolactin receptors.
Synonyms: Molgramostin antibody, Pluripoietin Alpha antibody, Sargramostim antibody, Colony stimulating factor antibody, CSF 2 antibody, CSF Alpha antibody, Burst Promoting Activity antibody
Gene ID 1437
UniProt P04141
Application Notes This antiserum against Human GM-CSF has been tested for use in neutralizations, ELISA and immunoblotting. Reactivity is also expected in neutralizations, radioimmunoassay and immunohistochemistry. The endotoxin content is estimated to be <10 pg/µl by the LAL method.
Restrictions For Research Use only
Format Liquid
Concentration 85 mg/mL
Storage -20 °C