HSPE1 antibody (AA 2-102) (Biotin)
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- Target See all HSPE1 Antibodies
- HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))
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Binding Specificity
- AA 2-102
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HSPE1 antibody is conjugated to Biotin
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Application
- ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human 10 kDa heat shock protein, mitochondrial protein (2-102AA)
- Isotype
- IgG
- Top Product
- Discover our top product HSPE1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Avoid freeze and thaw cycles.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))
- Alternative Name
- HSPE1 (HSPE1 Products)
- Synonyms
- CPN10 antibody, EPF antibody, GROES antibody, HSP10 antibody, groS antibody, Cpn10 antibody, cpn10 antibody, zgc:86747 antibody, hspe1 antibody, MGC89647 antibody, HSPE1 antibody, MITOCHONDRIAL CHAPERONIN 10 antibody, T15D22.2 antibody, T15D22_2 antibody, chaperonin 10 antibody, Dmel\\CG11267 antibody, Hsp10 antibody, anon-WO0118547.175 antibody, hsp10 antibody, crpB antibody, chpS antibody, 10kDa antibody, mt-cpn10 antibody, heat shock protein family E (Hsp10) member 1 antibody, molecular chaperone GroES antibody, chaperonin 10 kDa antibody, chaperonin, 10 kDa antibody, chaperonin-10 kDa antibody, heat shock protein family E member 1 antibody, heat shock 10 protein 1 antibody, heat shock protein family E (Hsp10) member 1 L homeolog antibody, heat shock 10kDa protein 1 (chaperonin 10) pseudogene antibody, 10 kd chaperonin antibody, chaperonin 10 antibody, Hsp10p antibody, co-chaperonin 10, mitochondrial antibody, CG11267 gene product from transcript CG11267-RA antibody, co-chaperonin GroES antibody, mitochondrial heat shock protein Hsp10 (predicted) antibody, chaperonin GroS antibody, Hsp10 10 kDa chaperonin GROES antibody, mitochondrial heat shock protein Hsp10 antibody, heat shock protein 10 antibody, heat shock protein 1 (chaperonin 10) antibody, heat shock 10kDa protein 1 (chaperonin 10) antibody, HSPE1 antibody, groES antibody, groES2 antibody, TP01_0190 antibody, Cag_1167 antibody, Bm1_56470 antibody, Hspe1 antibody, hspe1 antibody, hspe1.L antibody, LOC452179 antibody, Cpn10 antibody, CPN10 antibody, HSP10 antibody, CG11267 antibody, hsp10 antibody, groS antibody
- Background
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Background: Co-chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp60, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix (PubMed:7912672, PubMed:1346131, PubMed:11422376). The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10. This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components. Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein (Probable).
Aliases: 10 kDa chaperonin antibody, 10 kDa heat shock protein mitochondrial antibody, 10 kDa heat shock protein, mitochondrial antibody, CH10_HUMAN antibody, Chaperonin 10 antibody, Chaperonin 10 homolog antibody, CPN10 antibody, cpn10 homolog antibody, Early pregnancy factor antibody, Early-pregnancy factor antibody, EPF antibody, GROES antibody, GroES homolog antibody, Heat shock 10kD protein 1 chaperonin 10 antibody, Heat shock 10 kDa protein 1 antibody, Heat shock 10 kDa protein 1 chaperonin 10 antibody, Heat shock protein family E (Hsp10) member antibody, Heat-shock 10-kD protein antibody, Hsp10 antibody, Hspe1 antibody
- UniProt
- P61604
- Pathways
- Positive Regulation of Endopeptidase Activity
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