SAMSN1 antibody (C-Term)

Catalog No. ABIN1077391

Product Details anti-SAMSN1 Antibody

Target: SAMSN1 (SAM Domain, SH3 Domain and Nuclear Localization Signals, 1 (SAMSN1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAMSN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: At least two isoforms of SAMSN are known to exist.

Purification: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal SAMSN antibody was raised against an 18 amino acid peptide near the carboxy terminus of human SAMSN.

Isotype: IgG

Application Details

Application Notes: SAMSN antibody can be used for detection of SAMSN by Western blot at 1 - 2 μg/mL.

Comment:

(CT) SAM domain SH3 domain and nuclear localization signals 1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C

Storage Comment: SAMSN antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Expiry Date: 12 months

Target Details for SAMSN1

Target: SAMSN1 (SAM Domain, SH3 Domain and Nuclear Localization Signals, 1 (SAMSN1))

Alternative Name: SAMSN1 (SAMSN1 Products)

Synonyms: HACS1 antibody, NASH1 antibody, SASH2 antibody, SH3D6B antibody, SLy2 antibody, 4930571B16Rik antibody, 930571B16Rik antibody, Hacs1 antibody, Nash antibody, samsn1 antibody, wu:fa92h05 antibody, wu:fq83f12 antibody, SAMSN1 antibody, zgc:103427 antibody, SAM domain, SH3 domain and nuclear localization signals 1 antibody, SAM domain, SH3 domain and nuclear localization signals, 1 antibody, SAM domain, SH3 domain and nuclear localisation signals 1a antibody, SAM domain, SH3 domain and nuclear localisation signals 1b antibody, SAMSN1 antibody, Samsn1 antibody, samsn1a antibody, samsn1b antibody

Background: SAMSN (HACS1) is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains. It encodes a 441 amino acid protein that is differentially expressed in hematopoietic cells and malignancies including myeloid leukemia, lymphoma, and myeloma. SAMSN has restricted expression in human tissues. It has been shown to be up-regulated by B cell activation signals and is a participant in B cell activation and differentiation. SAMSN is an immunoinhibitory adaptor that might be a useful target for immune suppression therapy.
Synonyms: SAM domain SH3 domain and nuclear localization signals 1, SAMSN-1, NASH1, SASH2, SH3-SAM adaptor protein, SH3D6B, Hematopoietic adaptor containing SH3 and SAM domains 1, HACS1

Molecular Weight: 41 kDa

Gene ID: 64092

NCBI Accession: NP_071419