DHX36 antibody (C-Term)

Catalog No. ABIN1077418

Product Details anti-DHX36 Antibody

Target: DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHX36 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: At least four isoforms of DDX36 are known to exist, this antibody will detect the three longest isoforms.

Purification: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal DHX36 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human DHX36.

Isotype: IgG

Application Details

Application Notes: DHX36 antibody can be used for detection of DHX36 by Western blot at 0.5 - 1 μg/mL.

Comment:

(CT) DEAH box protein 36

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C

Storage Comment: DHX36 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Expiry Date: 12 months

Target Details for DHX36

Target: DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))

Alternative Name: DHX36 (DHX36 Products)

Synonyms: DHX57 antibody, DDX36 antibody, G4R1 antibody, MLEL1 antibody, RHAU antibody, 2810407E23Rik antibody, AI452301 antibody, AU022184 antibody, Ddx36 antibody, mKIAA1488 antibody, DEAH-box helicase 36 antibody, ATP-dependent RNA helicase DHX36 antibody, DEAH (Asp-Glu-Ala-His) box polypeptide 36 antibody, Dhx36 antibody, DHX36 antibody, dhx36 antibody, LOC100456222 antibody, LOC100633205 antibody

Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure. DHX36 (DEAH box protein 36), also known as MLE-like protein 1 and RNA helicase associated with AU-rich element ARE (RHAU), belongs to RNA helicase of the DEAH family and may function in sex development and spermatogenesis. It is expressed in testis and is evolutionary conserved with true orthologs in almost all animal species. DHX36 plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. DHX36 is required for early embryogenesis.
Synonyms: Asp-Glu-Ala-His

Molecular Weight: 111 kDa (calculated)

Gene ID: 170506

NCBI Accession: NP_065916

Pathways: Toll-Like Receptors Cascades