JAKMIP1 antibody

Catalog No. ABIN1077419

Product Details anti-JAKMIP1 Antibody

Target: JAKMIP1 (Janus Kinase and Microtubule Interacting Protein 1 (JAKMIP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAKMIP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Multiple isoforms of JAKMIP1 are known to exist. JAKMIP1 antibody is predicted to not cross-react with JAKMIP2.

Purification: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal JAKMIP1 antibody was raised against a 16 amino acid peptide near the center of human JAKMIP1.

Isotype: IgG

Application Details

Application Notes: JAKMIP1 antibody can be used for detection of JAKMIP1 by Western blot at 1 - 2 μg/mL.

Comment:

(IN) Janus kinase and microtubule interacting protein 1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C/-20 °C

Storage Comment: JAKMIP1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Expiry Date: 12 months

Target Details for JAKMIP1

Target: JAKMIP1 (Janus Kinase and Microtubule Interacting Protein 1 (JAKMIP1))

Alternative Name: JAKMIP1 (JAKMIP1 Products)

Synonyms: MGC81051 antibody, Gababrbp antibody, JAMIP1 antibody, MARLIN1 antibody, 5830437M04Rik antibody, C330021K24Rik antibody, Marlin-1 antibody, janus kinase and microtubule interacting protein 1 antibody, janus kinase and microtubule interacting protein 1 L homeolog antibody, janus kinase and microtubule-interacting protein 1 antibody, Celf_2690 antibody, JAKMIP1 antibody, jakmip1.L antibody, LOC100070079 antibody, jakmip1 antibody, LOC100432594 antibody, Jakmip1 antibody

Background: JAKMIP1, also known as Marlin-1, is a highly-conserved vertebrate-specific microtubule-associated protein that plays a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. JAKMIP1 is expressed predominantly in neuronal and lymphoid cells and colocalizes with microtubules. Multiple isoforms of JAKMIP1 are known to exist: isoforms 1 and 5 are also expressed in liver, lung and skeletal muscle, while isoforms 2-4 are specifically expressed in brain and retina. JAKMIP1 participates in polarized secretion in lymphocytes and it has been suggested to be a novel effector memory gene restraining T cell-mediated cytotoxicity. Dysregulation of JAKMIP1 gene expression is associated with genetic conditions linked to autism in humans.
Synonyms: Janus kinase and microtubule interacting protein 1, JAMIP1, Multiple alpha-helices and RNA-linker protein 1, Marlin-1, GABA-B receptor-binding protein, GABABRBP

Molecular Weight: 69 kDa (calculated)

Gene ID: 152789

NCBI Accession: NP_653321

Pathways: SARS-CoV-2 Protein Interactome