Lamin A/C antibody (LMNA) (AA 598-611)

Details for Product anti-LMNA Antibody No. ABIN108550, Supplier: Log in to see
Antigen
  • CDCD1
  • CDDC
  • CMD1A
  • CMT2B1
  • EMD2
  • FPL
  • FPLD
  • FPLD2
  • HGPS
  • IDC
  • LDP1
  • LFP
  • LGMD1B
  • LMN1
  • LMNC
  • LMNL1
  • PRO1
  • Dhe
  • 2459
  • 74/76
  • CG6944
  • D5
  • DM[[O]]
  • Dm
  • Dm(0)
  • Dm0
  • Dm1
  • Dm2
  • DmLamin
  • DmO
  • Dm[[0]]
  • Dm[[1]]
  • Dm[[2]]
  • Dm[[mit]]
  • Dm[[o]]
  • Dmel\\CG6944
  • Dmo
  • LAM
  • Lam Dm[[0]]
  • Lam(Dm0)
  • LamDm[[0]]
  • LamDm[[o]]
  • Lam[[Dm0]]
  • Lamin Dm[[0]]
  • jf27
  • l(2)04643
  • l(2)25Ec
  • l(2)gdh-7
  • l(2)gdh7
  • l(2)jf27
  • lam
  • lamDm0
  • lamDm[[0]]
  • lamin
  • lamin Dm0
  • lamin Dm[[0]]
  • misg
  • nlam
  • cb948
  • fk66d12
  • wu:fk66d12
  • lmna-A
  • fpl
  • idc
  • lfp
  • cddc
  • emd2
  • fpld
  • hgps
  • ldp1
  • lmn1
  • lmnc
  • pro1
  • cdcd1
  • cmd1a
  • cmt2b1
  • lgmd1b
  • Lamin-A
  • lamin-L(III)-like
  • lamin A/C
  • lamin A
  • Lamin
  • lamin A/C L homeolog
  • lamin-L(III)-like
  • LMNA
  • Lmna
  • Lam
  • lmna
  • lmna.L
  • LMINA
Alternatives
anti-Mouse (Murine) Lamin A/C antibody for Western Blotting
Epitope
AA 598-611
35
26
24
21
20
18
17
11
11
10
9
9
8
7
7
6
4
4
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Human, Monkey
445
271
235
103
53
51
24
21
14
10
8
7
5
4
3
3
3
2
1
1
1
Host
Mouse
232
220
5
1
Clonality (Clone)
Monoclonal ()
Conjugate
This Lamin A/C antibody is un-conjugated
13
12
10
7
7
7
7
6
6
6
6
6
6
6
5
5
4
4
4
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
408
210
199
163
118
113
77
73
55
17
14
11
2
2
1
1
Options
Supplier
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Supplier Product No.
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Immunogen Partially purified recombinant human lamin A.
Clone 133A2
Isotype IgG3 kappa
Specificity Recognizes an epitope located between residues 598-611 of lamin A, therefore it reacts exclusively with Lamin Aand absent from lamin C.As a result, this antibody recognizes lamin A but not lamin C, See Machiels et al 1997). Lamins do not appear to be universally distributed among different cell and tissue types. It has been tested in testis parenchyma and testicular germ cell tumours (See Machiels et al 1997). Other cell/tissue types have not been tested.
Purification Purfied
Plasmids, Primers & others Plasmids, Primers & others Lamin A/C products on genomics-online (e.g. as negative or positive controls)
Alternative Name Lamin A (LMNA Antibody Abstract)
Background Synonyms:
70 kDa lamin antibody,CDCD1 antibody,CDDC antibody,CMD1A antibody,CMT2B1 antibody,EMD2antibody,FPL antibody,FPLD antibody,HGPS antibody,IDC antibody,LAMIN A antibody,lamin A/Cantibody,LAMIN C antibody,Lamin-A/C antibody,LDP1 antibody,LFP antibody,LGMD1B antibody,LMN 1antibody,LMN A antibody,LMN C antibody,LMN1 antibody,LMNA antibody,LMNA_HUMAN antibody,LMNC antibody,NYREN 32 antigen antibody,PRO1 antibody,Renal carcinoma antigen NY-REN-32 antibody
Gene ID 404144, 4000, 16905
OMIM 150330
UniProt P48679
Pathways Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
Application Notes Optimal antibody dilution should be determined by titration, recommended range is 1:100 1:200 for flow cytometry, and for immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent, and 1:100 1:1000 for immunoblotting applications.
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Purified antibody in PBS containing 0.09 % sodium azide,
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Supplier Images
 image for anti-Lamin A/C (LMNA) (AA 598-611) antibody (ABIN108550) Immunostaining of lamin antibodies with human epidermis (a) is Lamin A (clone 133A2)
Product cited in: Krohne: "Lamins." in: Methods in cell biology, Vol. 78, pp. 573-96, 2005 (PubMed).

Pugh, Coates, Lane, Raymond, Quinlan: "Distinct nuclear assembly pathways for lamins A and C lead to their increase during quiescence in Swiss 3T3 cells." in: Journal of cell science, Vol. 110 ( Pt 19), pp. 2483-93, 1997 (PubMed).

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