Granulin antibody (AA 248-259)

Catalog No. ABIN1101900

Product Details anti-Granulin Antibody

Target: Granulin (GRN)

Binding Specificity: AA 248-259

Reactivity: Human, Mouse, Rat, Hamster, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This Granulin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Human GRN / Granulin. This antibody is expected to recognize the C-Terminal part of Granulin-3.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Mouse, Rat, Hamster (100%) Chimpanzee, Galago, Elephant, Panda, Bat, Rabbit (92%) Dog, Bovine, Horse, Guinea pig (83%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide PQDTVCDLIQSK from an internal of human GRN / Granulin (NP_002078.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Mouse, Rat, Hamster (100%), Chimpanzee, Galago, Elephant, Panda, Bat, Rabbit (92%), Dog, Bovine, Horse, Guinea pig (83%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:8000), WB (1 - 3 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:8000. Western blot: Approx 75kD band observed in lysates of cell lines A431, A549 and HeLa (calculated MW of 63.5kD according to NP_002078.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (He and Bateman, Cancer Res. 1999 Jul 1,59(13):3222-9. PMID: 10397269). Recommended concentration: 1-3 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Granulin

Target: Granulin (GRN)

Alternative Name: GRN / Progranulin / Granulin (GRN Products)

Synonyms: GRN antibody, grn antibody, wu:fb11g12 antibody, wu:fj18f05 antibody, MGC53354 antibody, DKFZp459H066 antibody, CLN11 antibody, GEP antibody, GP88 antibody, PCDGF antibody, PEPI antibody, PGRN antibody, epithelin antibody, acrogranin antibody, granulin precursor antibody, granulin a antibody, Granulins antibody, granulin L homeolog antibody, granulin antibody, GRN antibody, grna antibody, grn antibody, grn.L antibody, granulin antibody, ORF1 granulin antibody, Grn antibody

Target Type: Viral Protein

Background: Name/Gene ID: GRN
Family: Hormone

Synonyms: GRN, Acrogranin, CLN11, Epithelin precursor, GEP, gp88, Granulin, Granulin-epithelin, Granulins, PC cell-derived growth factor, PCDGF, PEPI, PGRN, Proepithelin, Progranulin

Gene ID: 2896

NCBI Accession: NP_002078

UniProt: P28799