RYK antibody (AA 98-110)

Catalog No. ABIN1104097

Product Details anti-RYK Antibody

Target: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Binding Specificity: AA 98-110

Reactivity: Human, Mouse, Rat, Cow, Dog, Bat, Horse, Monkey, Xenopus laevis

Host: Goat

Clonality: Polyclonal

Conjugate: This RYK antibody is un-conjugated

Application: ELISA

Specificity: Mouse RYK. This antibody is expected to recognize both reported isoforms (NP_038677.3, NP_001036072.1).

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Panda, Bovine, Dog, Bat, Horse, Turkey, Xenopus (100%) Opossum, Guinea pig (92%) Lizard (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-HAKSKVEYKLGFQ from an internal region of mouse RYK (NP_038677.3, NP_001036072.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Panda, Bovine, Dog, Bat, Horse, Turkey, Xenopus (100%), Opossum, Guinea pig (92%), Lizard (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:32000)

Usage: Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Preliminary experiments gave an approx 85kD band in Mouse Lung lysates after 0.1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 66.3kD according to NP_038677.3. The 85kD band was successfully blocked by incubation with the immunizing peptide.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for RYK

Target: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Alternative Name: RYK (RYK Products)

Synonyms: RYK antibody, jtk5 antibody, ryk1 antibody, jtk5a antibody, d3s3195 antibody, wu:fb37b12 antibody, wu:fi05b06 antibody, zgc:158381 antibody, MGC114645 antibody, D3S3195 antibody, JTK5 antibody, JTK5A antibody, RYK1 antibody, AW536699 antibody, ERK-3 antibody, Vik antibody, receptor-like tyrosine kinase antibody, receptor-like tyrosine kinase S homeolog antibody, tyrosine-protein kinase RYK antibody, RYK antibody, ryk antibody, ryk.S antibody, LOC100541106 antibody, Ryk antibody

Background: Name/Gene ID: RYK
Subfamily: RYK
Family: Protein Kinase

Synonyms: RYK, D3S3195, Hydroxyaryl-protein kinase, JTK5, JTK5A protein tyrosine kinase, RYK1, Vik, Tyrosine-protein kinase RYK, Receptor-like tyrosine kinase, JTK5A, Tyrosine kinase ryk

Gene ID: 6259

NCBI Accession: NP_038677, NP_001036072

UniProt: P34925

Pathways: RTK Signaling, WNT Signaling, Regulation of Cell Size