Aquaporin 5 antibody (C-Term)

Catalog No. ABIN1105431

Product Details anti-Aquaporin 5 Antibody

Target: Aquaporin 5 (AQP5)

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aquaporin 5 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody detects Aquaporin-5 at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Immunogen affinity purified

Immunogen: Synthetic peptide corresponding to a sequence at the C-terminal of human AQP5 .Remarks: Sequence is different to the related rat sequence by three amino acids.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for Aquaporin 5

Target: Aquaporin 5 (AQP5)

Alternative Name: Aquaporin-5 (AQP5 Products)

Synonyms: AQP-5 antibody, AQP5 antibody, LOC100231329 antibody, aquaporin 5 antibody, aquaporin-5 antibody, AQP5 antibody, Aqp5 antibody, LOC711804 antibody, LOC100231329 antibody

Background: Aquaporin 5, also known as AQP5, is a water channel protein. The aquaporins (AQPs) are a family of more than 10 homologous water transporting proteins expressed in many mammalian epithelia and endothelia. At least five AQPs are expressed in the eye: AQP0 (MIP) in lens fiber, AQP1 in cornea endothelium, ciliary and lens epithelia and trabecular meshwork, AQP3 in conjunctiva, AQP4 in ciliary epithelium and retinal Müller cells, and AQP5 in corneal and lacrimal gland epithelia.1 Among the seven human aquaporins cloned to date (AQPs 0-6), genes encoding the four most closely related aquaporins (AQP0, AQP2, AQP5, and AQP6) have been mapped to chromosome band 12q13, suggesting an aquaporin family gene cluster at this locus.2 Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions.Synonyms: AQP-5, AQP5

Gene ID: 362

NCBI Accession: NP_001642

UniProt: P55064