CLOCK antibody (Clock Homolog (Mouse))

Details for Product anti-CLOCK Antibody No. ABIN1106725
Antigen
  • CG7391
  • CLK
  • CLOCK
  • Dmel\\CG7391
  • Jerk
  • Jrk
  • PAS1
  • bHLHe10
  • clk
  • clock
  • dCLK
  • dCLK/JRK
  • dCLOCK
  • dClck
  • dClk
  • dClock
  • dclk
  • jrk
  • Xclk
  • XClock
  • zCLOCK1
  • zfCLOCK1
  • 5330400M04Rik
  • KAT13D
  • bHLHe8
  • mKIAA0334
  • Clock
  • clock circadian regulator
  • clock homolog (mouse)
  • clock circadian regulator a
  • circadian locomotor output cycles kaput
  • clock circadian regulator L homeolog
  • Clk
  • CLOCK
  • clock
  • clocka
  • Clock
  • clock.L
Reactivity
Human
110
57
44
4
3
3
3
3
3
3
3
2
1
1
1
Host
Mouse
80
33
7
1
Clonality (Clone)
Monoclonal ()
Conjugate
This CLOCK antibody is un-conjugated
4
2
2
2
2
2
2
2
2
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
97
51
36
21
10
10
8
5
3
3
2
2
2
1
1
Options
Clone 8F7
Isotype IgG1
Specificity This antibody reacts to CLOCK.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Plasmids, Primers & others Plasmids, Primers & others CLOCK products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name CLOCK (CLOCK Antibody Abstract)
Background This gene encodes a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1.Synonyms: BHLHE8, Circadian locomoter output cycles protein kaput, Class E basic helix-loop-helix protein 8, KIAA0334
Molecular Weight 95 kDa
Gene ID 9575
Pathways Regulation of Lipid Metabolism by PPARalpha, Photoperiodism
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
Image no. 1 for anti-Clock Homolog (Mouse) (CLOCK) antibody (ABIN1106725) anti-Clock Homolog (Mouse) (CLOCK) antibody (Image 1)
Image no. 2 for anti-Clock Homolog (Mouse) (CLOCK) antibody (ABIN1106725) anti-Clock Homolog (Mouse) (CLOCK) antibody (Image 2)
Background publications Kuo, Chen, Yeh, Hou, Chang, Hsu, Chang: "Disturbance of circadian gene expression in breast cancer." in: Virchows Archiv : an international journal of pathology, Vol. 454, Issue 4, pp. 467-74, 2009 (PubMed).

Takata, Nakashima, Takehara, Baba, Machida, Akitake, Ono, Hosokawa, Takahashi: "Detection of amyloid beta protein in the urine of Alzheimer's disease patients and healthy individuals." in: Neuroscience letters, Vol. 435, Issue 2, pp. 126-30, 2008 (PubMed).

Lee, Paik, Kang, Lim, Kim: "Allelic variants interaction of CLOCK gene and G-protein beta3 subunit gene with diurnal preference." in: Chronobiology international, Vol. 24, Issue 4, pp. 589-97, 2007 (PubMed).

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