FANCE antibody (Internal Region)

Catalog No. ABIN1107192

Product Details anti-FANCE Antibody

Target: FANCE (Fanconi Anemia, Complementation Group E (FANCE))

Binding Specificity: Internal Region

Reactivity: Human, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This FANCE antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequence: C-EHKSLESLAD GGS Remarks: Percent identity with other species by BLAST analysis: Human (100%), Gibbon (92%), Monkey (92%), Marmoset (85%), Bovine (85%), Rabbit (85%).

Specificity: This antibody detects FANCE.

Cross-Reactivity (Details): Species reactivity (expected):BovineSpecies reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic peptide from an internal region of Human FANCE (NP_068741.1).

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FANCE

Target: FANCE (Fanconi Anemia, Complementation Group E (FANCE))

Alternative Name: FANCE (FANCE Products)

Synonyms: FANCE antibody, fae antibody, face antibody, FACE antibody, FAE antibody, 2810451D06Rik antibody, AI415634 antibody, AW209126 antibody, RGD1561045 antibody, Fanconi anemia complementation group E antibody, Fanconi anemia, complementation group E antibody, FANCE antibody, fance antibody, Fance antibody

Background: FANCE promotes the nuclear accumulation of FANCC. FANCE protein is part of the FA nuclear complex, binding FANCC & FANCD2. It is required for the nuclear accumulation of FANCC and provides a bridge between the FA complex and FANCD2. FANCC mutants do not bind FANCE or prevent chromosome breakage.Synonyms: FACE, Fanconi anemia group E protein

Gene ID: 2178

NCBI Accession: NP_068741

Pathways: DNA Damage Repair