HERC4 antibody (Isoform 5, Middle Region)

Catalog No. ABIN1107512

Product Details anti-HERC4 Antibody

Target: HERC4 (Hect Domain and RLD 4 (HERC4))

Binding Specificity: Isoform 5, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HERC4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VGCGLRHTVF VLDDGTVYTC GCNDLGQLGH EKSRKKPEIL KVCQISRLYR

Cross-Reactivity (Details): Species reactivity (expected):Rat, Mouse.
Species reactivity (tested):Human.

Purification: Immunoaffinity column

Immunogen: Synthetic peptide corresponding to the middle region of human HERC4, Isoform 5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C for one month or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for HERC4

Target: HERC4 (Hect Domain and RLD 4 (HERC4))

Alternative Name: HERC4 (HERC4 Products)

Synonyms: 1700056O17Rik antibody, 4921531D01Rik antibody, 9530080M15Rik antibody, mKIAA1593 antibody, HECT and RLD domain containing E3 ubiquitin protein ligase 4 antibody, HECT and RLD domain containing E3 ubiquitin protein ligase 4 S homeolog antibody, hect domain and RLD 4 antibody, HERC4 antibody, herc4 antibody, herc4.S antibody, Herc4 antibody

Background: HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins.Synonyms: HECT domain and RCC1-like domain-containing protein 4, KIAA1593, Probable E3 ubiquitin-protein ligase HERC4

Molecular Weight: HERC4, Isoform 5: 13 kDa

Gene ID: 26091

NCBI Accession: NM_001017972