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IL23A antibody
IL23A
Reactivity: Human
IHC (p), Func
Host: Mouse
Monoclonal
B-Z23
unconjugated
Product Details anti-IL23A Antibody
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Target
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IL23A
(Interleukin 23, alpha subunit p19 (IL23A))
Reactivity
All reactivities for IL23A antibodies
Human
Host
All hosts for IL23A antibodies
Mouse
Clonality
All clonalities for IL23A antibodies
Monoclonal
Conjugate
All conjugates for IL23A antibodies
This IL23A antibody is un-conjugated
Application
All applications for IL23A antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func)
Specificity
This antibody recognizes both recombinant and natural IL-23, p19 sub-unit.
Purification
Ion Exchange Chromatography
Sterility
0.22 μm filtered
Immunogen
Recombinant Human IL-23 (sub-unit p19)
Clone
B-Z23
Isotype
IgG1
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Discover our top product IL23A Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL
Buffer
Phosphate-buffered saline. Sterile-filtered through 0.22 μm and treated to remove endotoxins. Carrier and preservative free.
Preservative
Without preservative
Storage
4 °C
Storage Comment
Store the antibody undiluted at 2-8 °C.
Target Details for IL23A
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Target
IL23A
(Interleukin 23, alpha subunit p19 (IL23A))
Alternative Name
Interleukin-23 alpha / IL23A (IL23A Products )
Synonyms
IL-23 antibody, IL-23A antibody, IL23P19 antibody, P19 antibody, SGRF antibody, FIL1 antibody, FIL1(ZETA) antibody, FIL1Z antibody, IL-1F7 antibody, IL-1H antibody, IL-1H4 antibody, IL-1RP1 antibody, IL-37 antibody, IL1F7 antibody, IL1H4 antibody, IL1RP1 antibody, p19 antibody, il23p19 antibody, IL23 antibody, interleukin 23 subunit alpha antibody, interleukin 37 antibody, interleukin 23, alpha subunit p19 antibody, IL23A antibody, IL37 antibody, Il23a antibody
Background
The p19 shares sequence similarity with IL-6 subfamily members and is distantly related to the p35 subunit of IL-12. It shows no biological activity by itself, instead, it combines with the p40 subunit of IL-12 to form a biologically active, composite cytokine, IL-23. IL-23 shares some in vivo functions with IL-12, including the activation of the transcription factor Stat4. Similar to IL-12, human IL-23 stimulates IFN-g production and proliferation in PHA blast T cells, as well as in CD45RO (memory) T cells. Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death.Synonyms: IL-23 subunit alpha, IL-23p19, Interleukin-23 subunit p19, SGRF
Gene ID
51561
NCBI Accession
NP_057668
UniProt
Q9NPF7
Pathways
Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Activated T Cell Proliferation
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