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IL-6 antibody

IL6 Reactivity: Human FACS, Func Host: Mouse Monoclonal B-E8 unconjugated
Catalog No. ABIN1107864
  • Target See all IL-6 (IL6) Antibodies
    IL-6 (IL6) (Interleukin 6 (IL6))
    Reactivity
    • 170
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    • 69
    • 28
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    • 15
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    Human
    Host
    • 195
    • 82
    • 54
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    Mouse
    Clonality
    • 213
    • 135
    • 1
    Monoclonal
    Conjugate
    • 190
    • 57
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    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    This IL-6 antibody is un-conjugated
    Application
    • 262
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    Flow Cytometry (FACS), Functional Studies (Func)
    Specificity
    Recognises both natural and recombinant Human IL-6
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Ion Exchange Chromatography
    Sterility
    0.22 μm filtered
    Immunogen
    Human recombinant IL-6.
    Clone
    B-E8
    Isotype
    IgG1
    Top Product
    Discover our top product IL6 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, Sterile-filtered through 0.22 μm and treated to remove endotoxins. Carrier and preservative free
    Preservative
    Without preservative
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    IL-6 (IL6) (Interleukin 6 (IL6))
    Alternative Name
    Interleukin-6 (IL6) (IL6 Products)
    Synonyms
    BSF2 antibody, HGF antibody, HSF antibody, IFNB2 antibody, IL-6 antibody, Il-6 antibody, ILg6 antibody, Ifnb2 antibody, il6 antibody, CHIL-6 antibody, interleukin 6 antibody, interleukin-6 antibody, IL6 antibody, Il6 antibody, il-6 antibody, IL-6 antibody
    Background
    Interleukin 6 (IL6) is a multifunctional 24 kDa protein originally discovered in the medium of RNA stimulated fibroblastoid cells. It is upregulated by IL1, TNF, PDGF, IFN beta, TNF alpha, NGF, IL17 and downregulated by glucocorticoids IL4, TGF beta. IL6 appears to be directly involved in the responses that occur after infection and cellular injury, and it may prove to be as important as IL1 and TNF alpha in regulating the acute phase response. IL6 has also been implicated in regulating adipose mass.Synonyms: B-cell stimulatory factor 2, BSF-2, CDF, CTL differentiation factor, Hybridoma growth factor, IFNB2, IL-6, Interferon beta-2
    Gene ID
    3569
    NCBI Accession
    NP_000591
    UniProt
    P05231
    Pathways
    TLR Signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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