KCNN4 antibody (C-Term)

Catalog No. ABIN1107942

Product Details anti-KCNN4 Antibody

Target: KCNN4 (Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNN4 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody detects KCNN4 at N-term. No cross reactivity with other proteins.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Immunogen affinity purified

Immunogen: Synthetic peptide corresponding to a sequence mapping at the C-terminal of human KCNN4 .Remarks: Sequence is identical to the related rat sequence.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for KCNN4

Target: KCNN4 (Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4))

Alternative Name: KCNN4 (KCNN4 Products)

Synonyms: KCa3.1 antibody, IK1 antibody, IKCA1 antibody, KCA4 antibody, SK4 antibody, hIKCa1 antibody, hKCa4 antibody, hSK4 antibody, rKCNN4c antibody, rSK4 antibody, SKCas antibody, mIKCa1 antibody, potassium calcium-activated channel subfamily N member 4 antibody, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 antibody, KCNN4 antibody, Kcnn4 antibody

Background: Intermediate conductance calcium-activated potassium channel protein 1 (KCNN4,Kca3.1) is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. KCNN4 may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.Synonyms: IK1, IKCA1, Intermediate conductance calcium-activated potassium channel protein 4, KCA4, KCNN4, KCa3.1, Putative Gardos channel, SK4

Gene ID: 3783

NCBI Accession: NP_002241

UniProt: O15554