Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
This antibody detects MIF at C-term. No cross reactivity with other proteins.
Cross-Reactivity (Details)
Species reactivity (tested):Human, mouse, rat
Purification
Immunogen affinity purified
Immunogen
Synthetic peptide corresponding to a sequence at the C-terminal of human MIF .Remarks: Sequence is different from the related rat and mouse sequence by single amino acid.
Macrophage migration inhibitory factor, MIF, is a cytokine released by T-lymphocytes, macrophages,and the pituitary gland that serves to integrate peripheral and central inflammatory responses. MIF gene has 3 exons separated by introns of only 189 and 95 bp, and covers less than 1 kb. Localization of the human gene for macrophage migration inhibitory factor (MIF) to chromosome 22q11.2 MIF plays a critical role in inflammatory diseases and atherogenesis.Synonyms: GLIF, Glycosylation-inhibiting factor, MMIF, Macrophage migration inhibitory factor, Phenylpyruvate tautomerase