PTPRR antibody

Catalog No. ABIN1108794

Product Details anti-PTPRR Antibody

Target: PTPRR (Protein tyrosine Phosphatase, Receptor Type, R (PTPRR))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This PTPRR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)

Specificity: This antibody is directed to the common part of these proteins (PTPBR7, PTP-SL and PTPPBSγ). Specificity has been tested in Immunoprecipitation, Immunohistochemistry and Immunoblotting. Crossreacts with the striatum enriched phosphatase (STEP) when using antibody in Immunoblotting (Figure 1). Additional tests for cross reactivity have not yet been performed.

Cross-Reactivity (Details): Species reactivity (tested):Mouse.

Purification: Protein A Chromatography

Immunogen: Recombinant PTP-SL-GST (NCBI accession number BN000437, expression vector pGEX-2T), expressed in E.coli.

Clone: 6A6

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Dissolve in a 100 mM Tris-HCl pH 8.0 buffer containing 0.05 % Sodium Azide

Concentration: 0.5 mg/mL (BSA concentration = 1%)

Buffer: 10 mM Ammonium Bicarbonate buffer

Precaution of Use: Be careful opening the vial since the antibody resides in a Vacuum.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for PTPRR

Target: PTPRR (Protein tyrosine Phosphatase, Receptor Type, R (PTPRR))

Alternative Name: PTPRR (PTPRR Products)

Synonyms: EC-PTP antibody, PCPTP1 antibody, PTP-SL antibody, PTPBR7 antibody, PTPRQ antibody, Pcptp1 antibody, ec-ptp antibody, pcptp1 antibody, ptp-sl antibody, ptpbr7 antibody, PTPRR antibody, Gmcp1 antibody, RPTPRR antibody, mPTP213 antibody, protein tyrosine phosphatase, receptor type R antibody, protein tyrosine phosphatase, receptor type, R antibody, protein tyrosine phosphatase, receptor type R L homeolog antibody, protein tyrosine phosphatase, receptor type, r antibody, receptor-type tyrosine-protein phosphatase R antibody, PTPRR antibody, Ptprr antibody, ptprr.L antibody, ptprr antibody, LOC100715069 antibody

Background: Protein tyrosine phosphatases (PTPs) are the enzymes that are instrumental in determining the spatial and temporal balance between the tyrosine phosphorylated and non-phosphorylated targets, and thus coordinately regulate these cellular responses to extracellular cues. The Ptprr gene gives rise to 4 different neuronal phosphatases which differ in length of their N-terminal part and subcellular localization. PTPBR7 (72 kDa) is receptor-like, PTP-SL (60 kDa) is membrane associated and PTPPBSγ (42 and 37 kDa) is a cytosolic phoaphatase.Synonyms: Ch-1PTPase, ECPTP, NC-PTPCOM1, PCPTP1, PTPRQ, Protein-tyrosine phosphatase PCPTP1, R-PTP-R, Receptor-type tyrosine-protein phosphatase R

Gene ID: 19279

NCBI Accession: NP_001155309

UniProt: Q62132