Teratocarcinoma-Derived Growth Factor 1 (TDGF1) antibody

Details for Product No. ABIN1109214
Target
Reactivity
Human
93
33
23
Host
Mouse
68
21
7
2
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
11
10
10
5
4
4
3
2
2
2
2
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
50
40
35
26
9
4
4
3
2
2
1
Options
Clone 3A6
Isotype IgG1
Specificity This antibody reacts to TDGF1.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Target
Alternative Name TDGF1 / CRIPTO (TDGF1 Antibody Abstract)
Background This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects.The cripto gene is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers. It could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.Tissue specificity: Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts.Synonyms: CRGF, Cripto-1 growth factor, Epidermal growth factor-like cripto protein CR1, Teratocarcinoma-derived growth factor 1
Gene ID 6997
Pathways EGFR Signaling Pathway
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Images
Image no. 1 for anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) antibody (ABIN1109214) anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) antibody (Image 1)
Image no. 2 for anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) antibody (ABIN1109214) anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) antibody (Image 2)