TRIM24 antibody (C-Term)

Catalog No. ABIN1109252

Product Details anti-TRIM24 Antibody

Target: TRIM24 (Tripartite Motif Containing 24 (TRIM24))

Binding Specificity: C-Term

Reactivity: Human, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This TRIM24 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequence: C-KRLKSIEERQ LLK

Specificity: This antibody is expected to recognise both reported isoforms, as represented by NP_003843.3 and NP_056989.2.

Cross-Reactivity (Details): Species reactivity (expected):Bovine.
Species reactivity (tested):Human.

Purification: Affinity Chromatography

Immunogen: Peptide with sequence from the C Terminus of the protein sequence according to NP_056989.2, NP_003843.3. Genename: TRIM24

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TRIM24

Target: TRIM24 (Tripartite Motif Containing 24 (TRIM24))

Alternative Name: TIF1-alpha / TRIM24 (TRIM24 Products)

Synonyms: TRIM24 antibody, PTC6 antibody, RNF82 antibody, TF1A antibody, TIF1 antibody, TIF1A antibody, TIF1ALPHA antibody, hTIF1 antibody, ptc6 antibody, rnf82 antibody, tf1a antibody, tif1 antibody, tif1a antibody, tif1alpha antibody, A130082H20Rik antibody, AI447469 antibody, D430004I05Rik antibody, TIF1-alpha antibody, TIF1alpha antibody, Tif1a antibody, tripartite motif containing 24 antibody, transcription intermediary factor 1-alpha antibody, tripartite motif containing 24 S homeolog antibody, tripartite motif-containing 24 antibody, TRIM24 antibody, trim24 antibody, LOC100548578 antibody, trim24.S antibody, Trim24 antibody

Background: The protein mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains (a RING, a B box type 1 and a B box type 2) and a coiled coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.Synonyms: RING finger protein 82, RNF82, TIF1, TIF1 alpha, TIF1A, Transcription intermediary factor 1-alpha, Tripartite motif-containing protein 24

Gene ID: 8805

NCBI Accession: NP_003843