Ceramide Synthase 2 antibody

Catalog No. ABIN1112817

Product Details anti-Ceramide Synthase 2 Antibody

Target: Ceramide Synthase 2 (CERS2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Ceramide Synthase 2 antibody is un-conjugated

Application: Western Blotting (WB)

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to the extracellular region of human LASS2 .

Clone: N39

Isotype: IgG2b

Application Details

Application Notes: WB (1:500-1000). Other applications have not been tested. The optimal dilutions should be determined by end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Expiry Date: 12 months

Target Details for Ceramide Synthase 2

Target: Ceramide Synthase 2 (CERS2)

Alternative Name: LAG1 longevity assurance homolog 2, LASS2 (CERS2 Products)

Synonyms: L3 antibody, LASS2 antibody, SP260 antibody, TMSG1 antibody, 0610013I17Rik antibody, AI225939 antibody, Lass2 antibody, TRH3 antibody, ceramide synthase 2 antibody, CERS2 antibody, Cers2 antibody

Background: Lass2 (LAG1 longevity assurance homolog 2) is a protein that in humans is encoded by the LASS2 gene. It has sequence similarity to yeast longevity assurance gene 1. And it is highly expressed in liver and kidney, which is very different from the expression of the previously identified human LAG1 homologue LAG1Hs-1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. LASS2 protein was able to inhibit the colony formation of human hepatoma cells in vitro, and it also plays a role in the regulation of cell growth.