Vangl1 antibody

Catalog No. ABIN1112943

Product Details anti-Vangl1 Antibody

Target: Vangl1 (Vang-Like 1 (Vangl1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Vangl1 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Purification: affinity purified

Isotype: IgG

Application Details

Application Notes: WB (1:500), ICC (1:100-200). Other applications have not been tested. The optimal dilutions should be determined by end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Expiry Date: 12 months

Target Details for Vangl1

Target: Vangl1 (Vang-Like 1 (Vangl1))

Alternative Name: Vang-Like Protein 1, VANGL1 (Vangl1 Products)

Synonyms: stb2 antibody, Kitenin antibody, Lpp2 antibody, Stb2 antibody, Stbm antibody, KITENIN antibody, LPP2 antibody, STB2 antibody, STBM2 antibody, VANGL planar cell polarity protein 1 antibody, vang-like 1 (van gogh, Drosophila) antibody, Vangl1 antibody, vangl1 antibody, VANGL1 antibody

Background: Vang-like protein 1 (VANGL1), also called Loop-tail protein 2 homolog (LPP2), is encoded by the VANGL1 gene, This gene contains 8 exons and it maps to chromosome 1p13 . The VANGL1 protein is a 524-amino acid , 65KD protein, which has 4 transmembrane domains and a C-terminal ser/thr-x-val motif. Yagyu et al. (2002) found that downregulation of VANGL1 expression suppressed growth of a human hepatoma cell line. Kalabis et al. (2006) found that VANGL1 overexpression enhanced this migration and wound closure in cultured cells.

Pathways: WNT Signaling