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EPO antibody

EPO Reactivity: Human WB, IHC (p), EIA, Func Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN112633
  • Target See all EPO Antibodies
    EPO (Erythropoietin (EPO))
    Reactivity
    • 128
    • 31
    • 23
    • 7
    • 6
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 113
    • 48
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 115
    • 50
    Polyclonal
    Conjugate
    • 89
    • 18
    • 14
    • 9
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EPO antibody is un-conjugated
    Application
    • 122
    • 78
    • 48
    • 40
    • 29
    • 14
    • 14
    • 13
    • 13
    • 13
    • 8
    • 8
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Functional Studies (Func)
    Specificity
    This antibody reacts with Erythropoietin, the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological levels of circulating erythrocyte mass. It is often used as a drug to treat anemia.
    Purification
    Affinity Chromatography on Protein A
    Immunogen
    CHO cell-derived, recombinant Human Erythropoietin.
    Top Product
    Discover our top product EPO Primary Antibody
  • Application Notes
    ELISA: 0.5-1 μg/mL. Western Blot: 1-2 μg/mL (Reducing and Non-Reducing Conditions). Functional Assays: The ND50 was determined to be approximately 1-3 μg/mL, in thepresence of 0.3 units/mL of rhEpo, using a Human factor dependant cell line. Immunohistochemistry on Paraffin Sections: 15 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.2, 0.09 % Sodium Azide, 5 % Trehalose
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    EPO (Erythropoietin (EPO))
    Alternative Name
    Erythropoietin / EPO (EPO Products)
    Synonyms
    EPO antibody, EP antibody, MVCD2 antibody, erythropoietin antibody, erythropoietin S homeolog antibody, erythropoietin a antibody, EPO antibody, epo antibody, epo.S antibody, Epo antibody, epoa antibody
    Target Type
    Hormone
    Background
    Human erythropoietin is member of the EPO/TPO family and encodes a secreted, glycosylated cytokine hormone composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. It is produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.Synonyms: Epoetin
    Gene ID
    2056
    NCBI Accession
    NP_000790
    UniProt
    P01588
    Pathways
    JAK-STAT Signaling, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity
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