APOA2
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Can be used to detect the existence of Apo AII in plasma and lipoproteins, forimmunoassay, immunoblot, enzyme conjugation or biotinylation. Dilution for immunoblotand ELISA: 5,000-40,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
1 mg/mL (OD280nm, E0.1% = 1.35)
Buffer
75 mM PBS, 75 mM NaCl, pH 7.2 with 0.02 % sodium azide as preservative.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Target
APOA2
(Apolipoprotein A-II (APOA2))
Alternative Name
Apolipoprotein A II (Apo AII)
Background
Apolipoprotein A II is the second most abundant protein of the high density lipoprotein particles. The apolipoprotein A II gene consists of 4 exons and 3 introns. The four exons encode the 5' untranslated region, pre peptide, a short N terminal domain and a C terminal domain composed of a variable number of lipid binding amphipathic helices. Familial apolipoprotein A II deficiency may result from a splice junction alteration which blocks splicing of intron 3 from the primary transcript and result in the formation of a non functional mRNA.Synonyms: APOA2, Apo-AII, ApoA-II, Apolipoprotein A-II, Apolipoprotein A2