PLG antibody
Quick Overview for PLG antibody (ABIN115500)
Target
See all PLG AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- The antibody was raised in rabbits by immunization with the Human Angiostatin from human plasma.
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Purification
- Immunoaffinity chromatography
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Application Notes
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ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Reconstitution
- Restore with 0.1 mL of deionized water. Slight turbidity may occur after reconstitution, which does not affect activity of the antibody. In this case clarify the solution by centrifugation.
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Concentration
- 1.0 mg/mL
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Buffer
- 0.05 M Phosphate buffer, 0.5 M NaCl, pH 7.2. Azie Free, None
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Preservative
- Azide free
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.
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Expiry Date
- 6 months
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- PLG (Plasminogen (PLG))
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Alternative Name
- Plasminogen / PLG
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Background
- Angiostatin, an internal fragment of plasminogen, is a potent inhibitor of angiogenesis, which selectively inhibits endothelial cell proliferation. Angiostatin potently inhibits tumor growth and can maintain metastatic and primary tumors in a dormant state. It is defined by a balance of proliferation and apoptosis of the tumor cells and is composed of plasminogen first four cringle structures. This molecule is generated by proteolytic cleavage of plasminogen. Recombinant angiostatin has 260 amino acids, residues 97-357 of human proplasminogen, and a calculated molecular mass of 29.8 kDa. The Human Angiostatin contains Kringle 1 - 4 and part of 5.Synonyms: PLG, Plasminogen
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Gene ID
- 5340
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NCBI Accession
- NP_000292
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UniProt
- P00747
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Pathways
- Complement System, Lipid Metabolism
Target
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