CXCL11 antibody (Biotin)

Catalog No. ABIN116295

Product Details anti-CXCL11 Antibody (Biotin)

Target: CXCL11 (Chemokine (C-X-C Motif) Ligand 11 (CXCL11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCL11 antibody is conjugated to Biotin

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: Human I-TAC

Purification: Affinity chromatography.

Immunogen: Highly pure (>98%) recombinant hI-TAC.

Application Details

Application Notes: ELISA: To detect hI-TAC by direct ELISA (using 100 l/well antibody solution) this antibodycan be used at a concentration of 0.15 - 0.30 μg/mL. Used in conjunction with compatiblesecondary reagents, allows the detection of at least 0.2 ng/well of recombinant hI-TAC. Western Blot: To detect hI-TAC by Western Blot analysis this antibody can be used at aconcentration of 0.1 - 0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hI-TAC is 1.5 - 3.0 ng/lane, under either reducing ornon-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS, pH 7.2 without preservatives.

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing. Centrifuge vial prior to opening!

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4-8 °C for up to one month or in small aliquots at -20 °C for longer.

Target Details for CXCL11

Target: CXCL11 (Chemokine (C-X-C Motif) Ligand 11 (CXCL11))

Alternative Name: CXCL11 / ITAC (CXCL11 Products)

Synonyms: H174 antibody, I-TAC antibody, IP-9 antibody, IP9 antibody, SCYB11 antibody, SCYB9B antibody, b-R1 antibody, Cxc11 antibody, I-tac antibody, Ip9 antibody, Itac antibody, Scyb11 antibody, Scyb9b antibody, betaR1 antibody, C-X-C motif chemokine ligand 11 antibody, chemokine (C-X-C motif) ligand 11 antibody, CXCL11 antibody, Cxcl11 antibody

Background: This member of the the intercrine alpha (chemokine CxC) family is chemotactive for interleukin-activated T cells but not unstimulated T cells, neutrophils or monocytes. It induces calcium release in activated T cells and binds to CXCR3. It may play an important role in CNS diseases which involve T cell recruitment and in skin immune responses. It is expressed at high levels in peripheral blood leukocytes, pancreas and liver astrocytes and at moderate levels in thymus, spleen and lung. It is induced by interferon gamma and interferon beta.Synonyms: Beta-R1, C-X-C motif chemokine 11, H174, I-TAC, IP-9, Interferon-gamma-inducible protein 9, Interferon-inducible T-cell alpha chemoattractant, SCYB11, SCYB9B, Small-inducible cytokine B11

Gene ID: 6373

NCBI Accession: NP_005400

UniProt: O14625