CLEC11A antibody

Catalog No. ABIN116317

Product Details anti-CLEC11A Antibody

Target: CLEC11A (C-Type Lectin Domain Family 11, Member A (CLEC11A))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CLEC11A antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)

Specificity: Stem Cell Growth Factor beta (SCGF-beta)

Purification: Affinity chromatography.

Immunogen: Highly pure (>98%) recombinant hSCGF-beta (human Stem Cell Growth Factor beta).

Application Details

Application Notes: Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofHuman SCGF-beta (30.0 ng/mL), a concentration of 2.5-5.0 μg/mL of this antibody isrequired. Sandwich ELISA: To detect Human SCGF-beta by Sandwich ELISA (using 100 μL/wellantibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required. Thisantigen affinity purified antibody, in conjunction with Biotinylated anti-Human SCGF-beta(PP1106B1 or PP1106B2) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of recombinant Human SCGF-beta. Western Blot: To detect Human SCGF-beta by Western Blot analysis this antibody can beused at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondaryreagents the detection limit for recombinant Human SCGF-beta is 1.5-3.0 ng/lane, undereither reducing or non-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in sterile water to a concentration of 0.1-1.0 mg/mL

Buffer: PBS, pH 7.2 without preservatives.

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for CLEC11A

Target: CLEC11A (C-Type Lectin Domain Family 11, Member A (CLEC11A))

Alternative Name: SCGF / CLEC11A (CLEC11A Products)

Synonyms: CLEC11A antibody, CLECSF3 antibody, LSLCL antibody, P47 antibody, SCGF antibody, AW457320 antibody, Clecsf3 antibody, Scgf antibody, C-type lectin domain containing 11A antibody, C-type lectin domain family 11, member a antibody, CLEC11A antibody, Clec11a antibody

Background: This cytokine stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. It acts synergistically with other cytokines, including IL3, GCSF, GMCSF and FLT3 ligand and suppresses SCF-stimulated erythrocyte proliferation.Synonyms: C-type lectin domain family 11 member A, C-type lectin superfamily member 3, CLECSF3, LSLCL, Lymphocyte secreted C-type lectin, Stem cell growth factor, p47

Gene ID: 6320

NCBI Accession: NP_002966

UniProt: Q9Y240