IL23A antibody

Catalog No. ABIN1169135

Product Details anti-IL23A Antibody

Target: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This IL23A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Recognizes human IL-23p19.

Cross-Reactivity: Human

Sterility: 0.2 μm filtered

Immunogen: Recombinant human IL-23p19.

Clone: I 178G

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

Target Details for IL23A

Target: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Alternative Name: IL-23p19 (IL23A Products)

Synonyms: IL-23 antibody, IL-23A antibody, IL23P19 antibody, P19 antibody, SGRF antibody, FIL1 antibody, FIL1(ZETA) antibody, FIL1Z antibody, IL-1F7 antibody, IL-1H antibody, IL-1H4 antibody, IL-1RP1 antibody, IL-37 antibody, IL1F7 antibody, IL1H4 antibody, IL1RP1 antibody, p19 antibody, il23p19 antibody, IL23 antibody, interleukin 23 subunit alpha antibody, interleukin 37 antibody, interleukin 23, alpha subunit p19 antibody, IL23A antibody, IL37 antibody, Il23a antibody

Background: IL-23p19 associates with IL-12b to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 binds to an heterodimeric receptor complex composed of IL-12RB1 and IL-23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

UniProt: Q9NPF7

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation