IL1RL1 antibody

Catalog No. ABIN1169348

Product Details anti-IL1RL1 Antibody

Target: IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL1RL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: Recognizes human ST2.

Cross-Reactivity: Human

Sterility: 0.2 μm filtered

Immunogen: Recombinant human soluble ST2.

Clone: ST33868

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

Target Details for IL1RL1

Target: IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

Alternative Name: ST2 (IL1RL1 Products)

Synonyms: DER4 antibody, Fit-1 antibody, Ly84 antibody, ST2L antibody, St2 antibody, St2-rs1 antibody, T1 antibody, T1/ST2 antibody, FIT-1 antibody, IL33R antibody, ST2 antibody, ST2V antibody, FIT1 antibody, interleukin 1 receptor-like 1 antibody, interleukin 1 receptor like 1 antibody, Il1rl1 antibody, IL1RL1 antibody

Background: The ST2 gene was originally identified as a gene induced by serum or oncogene expression in fibroblasts. The gene produces a shorter soluble secreted form (ST2) and a longer, transmembrane form (ST2L) by alternative splicing. Soluble ST2 has been shown to downregulate the expression of TLR1 and TLR4. ST2L negatively regulates TLR4 signaling and induces endotoxin tolerance, and enhances Th2 responses. IL-33 is the specific ligand for ST2L.

UniProt: Q01638