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Granulin antibody

GRN Reactivity: Mouse WB, ELISA Host: Rat Polyclonal unconjugated
Catalog No. ABIN1169392
  • Target See all Granulin (GRN) Antibodies
    Granulin (GRN)
    Reactivity
    • 51
    • 8
    • 4
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 42
    • 9
    • 4
    • 2
    • 1
    Rat
    Clonality
    • 47
    • 11
    Polyclonal
    Conjugate
    • 34
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Granulin antibody is un-conjugated
    Application
    • 51
    • 18
    • 17
    • 13
    • 13
    • 10
    • 7
    • 7
    • 6
    • 3
    • 3
    Western Blotting (WB), ELISA
    Specificity
    Recognizes mouse progranulin. Detects a band of ~90 kDa by Western blot.
    Cross-Reactivity
    Mouse (Murine)
    Cross-Reactivity (Details)
    Weakly cross-reacts with human progranulin.
    Sterility
    0.2 μm filtered
    Immunogen
    Recombinant mouse progranulin.
    Top Product
    Discover our top product GRN Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
    Preservative
    Without preservative
    Storage
    4 °C,-20 °C
    Storage Comment
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Expiry Date
    6 months
  • Target
    Granulin (GRN)
    Alternative Name
    Progranulin (GRN Products)
    Synonyms
    GRN antibody, grn antibody, wu:fb11g12 antibody, wu:fj18f05 antibody, MGC53354 antibody, DKFZp459H066 antibody, CLN11 antibody, GEP antibody, GP88 antibody, PCDGF antibody, PEPI antibody, PGRN antibody, epithelin antibody, acrogranin antibody, granulin precursor antibody, granulin a antibody, Granulins antibody, granulin L homeolog antibody, granulin antibody, GRN antibody, grna antibody, grn antibody, grn.L antibody, granulin antibody, ORF1 granulin antibody, Grn antibody
    Target Type
    Viral Protein
    Background
    Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimer's Disease (AD) and potentially for MCI (Mild Cognitive Impairment). Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.
    UniProt
    P28798
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