ITGA5 antibody (Integrin, alpha 5 (Fibronectin Receptor, alpha Polypeptide))

Details for Product anti-ITGA5 Antibody No. ABIN1177342, Supplier: Log in to see
Antigen
  • ITGA5
  • Cd49e
  • Fnra
  • VLA5
  • CD49e
  • FNRA
  • VLA5A
  • Itga5_retired
  • integrin subunit alpha 5
  • integrin alpha 5 (fibronectin receptor alpha)
  • ITGA5
  • Itga5
Alternatives
anti-Human ITGA5 antibody for Flow Cytometry
Reactivity
Human, Pig (Porcine)
211
167
52
5
4
3
3
2
1
1
Host
Mouse
137
76
75
12
3
2
1
1
1
Clonality (Clone)
Monoclonal ()
Conjugate
This ITGA5 antibody is un-conjugated
30
23
19
7
6
6
5
4
3
3
3
2
2
1
1
1
1
1
1
Application
Functional Studies (Func), Flow Cytometry (FACS), Immunoprecipitation (IP)
183
145
93
79
33
33
20
18
13
9
7
6
5
4
3
2
2
2
1
1
Options
Supplier
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Supplier Product No.
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Brand BD Pharmingen™
Clone VC5
Isotype IgG1, kappa
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Sterility 0.2 μm filtered
Endotoxin Level Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
Plasmids, Primers & others Plasmids, Primers & others ITGA5 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name CD49e (ITGA5 Antibody Abstract)
Background Reacts with the alpha5 integrin, a dimer of 135/25 kDa, that associates with beta1 integrin (CD29) to form VLA-5, a well-established fibronectin receptor that is expressed on many cell types, including fibroblasts, endothelial cells, epithelial cells, platelets, peripheral T cells, the myeloid cell line U937, K562 and some melanoma cell lines. This clone does not inhibit alpha5beta1/ligand binding. This antibody is routinely tested by flow cytometric analysis.
Synonyms: Integrin alpha5 chain
Pathways Integrin Complex
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
Preservative Azide free
Storage 4 °C
Storage Comment Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Supplier Images
Binding Studies (Bind) image for anti-Integrin, alpha 5 (Fibronectin Receptor, alpha Polypeptide) (ITGA5) antibody (ABIN1177342) anti-Integrin, alpha 5 (Fibronectin Receptor, alpha Polypeptide) (ITGA5) antibody
Product cited in: Tran Van Nhieu, Isberg: "Bacterial internalization mediated by beta 1 chain integrins is determined by ligand affinity and receptor density." in: The EMBO journal, Vol. 12, Issue 5, pp. 1887-95, 1993 (PubMed).

Van Nhieu, Isberg: "The Yersinia pseudotuberculosis invasin protein and human fibronectin bind to mutually exclusive sites on the alpha 5 beta 1 integrin receptor." in: The Journal of biological chemistry, Vol. 266, Issue 36, pp. 24367-75, 1992 (PubMed).

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