NTSR1 antibody

Catalog No. ABIN122341

Product Details anti-NTSR1 Antibody

Target: NTSR1 (Neurotensin Receptor 1 (High Affinity) (NTSR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NTSR1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Reacts with Neurotensin Receptor Type 1 (family: GPCR, subfamily: Neurotensin)

Purification: Peptide immunogen affinity column

Immunogen: Synthetic peptide - KLH conjugated

Application Details

Application Notes: Immunohistochemistry with formalin fixed paraffin embedded tissues: 16 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-80 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for NTSR1

Target: NTSR1 (Neurotensin Receptor 1 (High Affinity) (NTSR1))

Alternative Name: Neurotensin Receptor 1 (NTSR1 Products)

Synonyms: NTSR1 antibody, Ntsr antibody, NT-1R antibody, NTR-1 antibody, NTR1 antibody, NTR antibody, neurotensin receptor 1 antibody, neurotensin receptor 1 (high affinity) antibody, NTSR1 antibody, Ntsr1 antibody

Background: NTR1, a Neurotensin Receptor, activates a phosphatidylinositol-calcium second messenger system in the central and peripheral nervous systems. It mediates the functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. Neurotensin Receptor 1 expression is enhanced in pancreatic cancer and in chronic pancreatitis. Two differentially glycosylated forms of the NT1 receptor have been identified in rats, a 54- kDa form that is expressed from birth to adulthood, and a 52- kDa form only detected at 10 and 15 days postnatal. NTR1 has been reported in brain, pancreas, and small intestine. ESTs have been isolated from brain and colon libraries.Synonyms: High-affinity levocabastine-insensitive neurotensin, NT-R-1, NTR1, NTRR, NTSR1

Gene ID: 4923