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ING5 antibody (AA 127-140)

ING5 Reactivity: Human WB, ELISA Host: Goat Polyclonal unconjugated
Catalog No. ABIN129552
  • Target See all ING5 Antibodies
    ING5 (Inhibitor of Growth Family, Member 5 (ING5))
    Binding Specificity
    • 7
    • 7
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 127-140
    Reactivity
    • 39
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 36
    • 3
    Goat
    Clonality
    • 39
    Polyclonal
    Conjugate
    • 19
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ING5 antibody is un-conjugated
    Application
    • 27
    • 20
    • 6
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Characteristics
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    This affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 127-140 of Human p28 ING5protein (Inhibitor of growth family, member 5). This sequence shows homology to and 2 for ING5.
    Isotype
    IgG
    Top Product
    Discover our top product ING5 Primary Antibody
  • Application Notes
    This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 28 kDa or 26 kDa in size corresponding to variants of ING5 by western blotting in the appropriate cell lysate or extract.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.52 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Iizuka, Sarmento, Sekiya, Scrable, Allis, Smith: "Hbo1 Links p53-dependent stress signaling to DNA replication licensing." in: Molecular and cellular biology, Vol. 28, Issue 1, pp. 140-53, (2007) (PubMed).

  • Target
    ING5 (Inhibitor of Growth Family, Member 5 (ING5))
    Alternative Name
    p28 ING5 (ING5 Products)
    Synonyms
    p28ING5 antibody, 1700001C14Rik antibody, 1700027H23Rik antibody, 1810018M11Rik antibody, AI225768 antibody, p28ing5 antibody, MGC76007 antibody, ING5 antibody, MGC133862 antibody, ING1 antibody, p33 antibody, si:busm1-40g1.1 antibody, si:dz40g1.1 antibody, wu:fc94a02 antibody, zgc:100910 antibody, ing5 antibody, inhibitor of growth family member 5 antibody, inhibitor of growth family, member 5 antibody, inhibitor of growth family member 5 L homeolog antibody, inhibitor of growth family, member 5b antibody, inhibitor of growth family, member 5a antibody, ING5 antibody, Ing5 antibody, ing5 antibody, ing5.L antibody, ing5b antibody, ing5a antibody
    Background
    P28 ING5 is a tumor suppressor protein similar to ING1 that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway.  Multiple alternatively spliced transcript variants have been observed.  The accession number listed below is for variant (1) encodes the longest isoform.
    Synonyms: ING5 antibody, Inhibitor of growth family member 5 antibody
    Gene ID
    84289, 18644730
    UniProt
    Q8WYH8
    Pathways
    Chromatin Binding
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