AP3D1 antibody (AA 686-698)

Catalog No. ABIN129555

Product Details anti-AP3D1 Antibody

Target: AP3D1 (Adaptor-Related Protein Complex 3, delta 1 Subunit (AP3D1))

Binding Specificity: AA 686-698

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This AP3D1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Chimpanzee, Chicken

Characteristics: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 686-698 of Human AP3D1.

Isotype: IgG

Application Details

Application Notes: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 130 kDa in size corresponding to AP3D1 by western blotting in the appropriate cell lysate or extract. Multiple isoforms exist for this protein.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.6 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-AP3D1 antibody (ABIN129555)

Zheng, Saunders, Sorensen, Waxmonsky, Conner: "Notch signaling from the endosome requires a conserved dileucine motif." in: Molecular biology of the cell, Vol. 24, Issue 3, pp. 297-307, (2013) (PubMed).

Concepcion, Flores-Garcuia, Hamilton: "Multipotent genetic suppression of retrotransposon-induced mutations by Nxf1 through fine-tuning of alternative splicing." in: PLoS genetics, Vol. 5, Issue 5, pp. e1000484, (2009) (PubMed).

Target Details for AP3D1

Target: AP3D1 (Adaptor-Related Protein Complex 3, delta 1 Subunit (AP3D1))

Alternative Name: AP3D1 (AP3D1 Products)

Synonyms: wu:fj51g01 antibody, si:ch211-129c21.6 antibody, ADTD antibody, hBLVR antibody, AA407035 antibody, Ap3d antibody, Bolvr antibody, mBLVR1 antibody, mh antibody, mocha antibody, BLVR antibody, adaptor-related protein complex 3, delta 1 subunit antibody, AP-3 complex subunit delta-1 antibody, adaptor related protein complex 3 delta 1 subunit antibody, ap3d1 antibody, EDI_172030 antibody, EHI_158840 antibody, Tsp_04773 antibody, AP3D1 antibody, Ap3d1 antibody

Background: AP3D1 (also known as Delta-adaptin 3, AP-3 complex delta subunit and Delta-adaptin) is a subunit of the AP3 adaptor-like complex, which is not associated with clathrin. The AP3D1 subunit is implicated in intracellular biogenesis and trafficking of pigment granules and possibly platelet dense granules and neurotransmitter vesicles.
Synonyms: AP-3 complex subunit delta-1 Adapter-related protein complex 3 subunit delta-1 AP-3 complex subunit delta Delta-adaptin

Gene ID: 8943, 117553580

UniProt: O14617