BACH1 antibody (Isoform 1)

Catalog No. ABIN129585

Product Details anti-BACH1 Antibody

Target: BACH1 (BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1))

Binding Specificity: AA 92-104, Isoform 1

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BACH1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Characteristics: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to amino acids 92-104 of of human BACH1 protein.
Immunogentype:Recombinant

Isotype: IgG

Application Details

Application Notes: This affinity purified antibody has been tested for use in ELISA and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 105 -140 kDa in size corresponding to isoforms of BACH1 protein by western blotting in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for BACH1

Target: BACH1 (BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1))

Alternative Name: BACH1 (BACH1 Products)

Synonyms: zgc:112205 antibody, BACH1 antibody, 6230421P05Rik antibody, AI323795 antibody, BACH-1 antibody, BTB domain and CNC homolog 1 antibody, BTB and CNC homology 1, basic leucine zipper transcription factor 1 b antibody, BTB and CNC homology 1, basic leucine zipper transcription factor 1 antibody, BACH1 antibody, bach1b antibody, bach1 antibody, Bach1 antibody

Background: BACH1 (also known as BRCA1 interacting protein C-terminal helicase 1, BRCA1-interacting protein 1 and BRCA1-associated C-terminal helicase 1) is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). The BACH1 gene may be a target of germline cancer-inducing mutations.   BACH1 is localized within the nucleus and functions as a DNA-dependent ATPase and 5' to 3' DNA helicase.  Two isoforms have been identified for this protein.
Synonyms: BRAC 1 Associated C Terminal Helicase 1 antibody, BRCA 1 Interacting Protein 1 antibody, BRCA1 binding helicase like protein BACH1 antibody, BRCA1 interacting protein C terminal helicase 1 antibody, BRIP 1 antibody

Gene ID: 83990, 14042978

UniProt: Q9BX63