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MARK2 antibody (Isoform A, pThr595)

MARK2 Reactivity: Human ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN129661
  • Target See all MARK2 Antibodies
    MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))
    Binding Specificity
    • 13
    • 8
    • 8
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Isoform A, pThr595
    Reactivity
    • 73
    • 49
    • 40
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 69
    • 3
    • 1
    Rabbit
    Clonality
    • 61
    • 12
    Polyclonal
    Conjugate
    • 36
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This MARK2 antibody is un-conjugated
    Application
    • 50
    • 36
    • 22
    • 16
    • 11
    • 10
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Cross-Reactivity
    Dog (Canine), Sheep (Ovine), Mouse (Murine), Rat (Rattus)
    Characteristics
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids surrounding T595 of Human MARK2 . The immunogen peptide was phosphorylated at the residue corresponding to T595.
    Isotype
    IgG
    Top Product
    Discover our top product MARK2 Primary Antibody
  • Application Notes
    This affinity purified antibody has been tested for use in ELISA and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 83 kDa corresponding to MARK2 by western blotting in the appropriate cell lysate or extract.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.6 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))
    Alternative Name
    MARK2 (MARK2 Products)
    Synonyms
    EMK-1 antibody, EMK1 antibody, PAR-1 antibody, Par-1b antibody, Par1b antibody, AU024026 antibody, Emk antibody, Par-1 antibody, mKIAA4207 antibody, microtubule affinity regulating kinase 2 antibody, MAP/microtubule affinity regulating kinase 2 antibody, MARK2 antibody, Mark2 antibody
    Background
    This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. This antibody recognizes a regulatory phosphorylation on a kinase that is critical to regulation of microtubules, cell cycle and immune responses.  MARK2 refers to MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens].  EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule stability and cancer.  Several cDNA clones have been isolated that encode two isoforms of the human ser/thr protein kinase EMK1 called MARK2.  These isoforms were characterized by the presence of a 162-bp alternative exon that gives rise to two forms, one containing the exon and the other one lacking it.  Both forms were found to be co-expressed in a number of selected cell lines and tissue samples.  Human MARK2 was shown to be encoded by a single mRNA that is ubiquitously expressed.  This transcription variant includes the alternative exon in the coding region and therefore codes for a longer protein.   Multiple splice variants exist for this protein.
    Synonyms: ELKL motif kinase antibody, EMK1 antibody, MAP/microtubule affinity regulating kinase 2 antibody, PAR1 homolog antibody, Serine/threonine protein kinase MARK2 antibod
    Gene ID
    2011
    UniProt
    Q7KZI7, Q7KZ17
    Pathways
    SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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