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RT1-BB antibody (PE)

RT1-BB Reactivity: Rat, Mouse FACS Host: Mouse Monoclonal OX-3 PE
Catalog No. ABIN133227
  • Target See all RT1-BB Antibodies
    RT1-BB (RT1 Class II, Locus Bb (RT1-BB))
    Reactivity
    Rat, Mouse
    Host
    • 4
    Mouse
    Clonality
    • 4
    Monoclonal
    Conjugate
    • 2
    • 1
    • 1
    This RT1-BB antibody is conjugated to PE
    Application
    • 4
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    Rat RT1.Bu ( Rat Ia-polymorphic)
    Purification
    Purified from ascitic fluid via Protein G Chromatography.
    Immunogen
    Rat thymocyte membrane glycoprotein . Fusion Partner: P3-NS1-1-Ag4 (NS1/1) . Donor: BALB/c spleen
    Clone
    OX-3
    Isotype
    IgG1
    Top Product
    Discover our top product RT1-BB Primary Antibody
  • Restrictions
    For Research Use only
  • Concentration
    0.1 mg/ml
    Buffer
    R-PE conjugated Ig buffered in PBS, 0.02% NaN and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml. (Purified from ascitic fluid via Protein G Chromatography)
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Target
    RT1-BB (RT1 Class II, Locus Bb (RT1-BB))
    Alternative Name
    RT1.B (RT1-BB Products)
    Synonyms
    RT1.B antibody, RT1 class II, locus Bb antibody, RT1-Bb antibody
    Background
    Anti-rat RT1.Bu monoclonal antibody recognizes a polymorphic determinant on rat Ia present on Lewis, Wistar, and AO rat strains (although it is apparently expressed in lower amounts in AO rats) but not BN, ACI, DA, or PVG/ c strains (1,2). This antibody also cross-reacts with mouse strains (MHC haplotypes b and s ) and analysis of recombinant mouse strains shows that the determinant maps to the I-A region and correlates with mouse Ia specificity 9 (1). ABIN133227recognizes Ia antigens on approximately 18% of thymocytes but does not significantly label the majority of peripheral T lymphocytes (1,3,4). Thus, ABIN133227is particularly useful for distinguishing Ia positive cells from different rat strains and has been used in the recognition of cells of donor origin in bone marrow reconstituted radiation chimeras (3,4).
    Pathways
    Production of Molecular Mediator of Immune Response
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