CD200 antibody (FITC)

Catalog No. ABIN133412

Product Details anti-CD200 Antibody (FITC)

Target: CD200

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD200 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Specificity: Rat thymocytes, brain, follicular dendritic cells in lymphoid organs, vascular endothelium, and at low levels on some smooth muscle and B lymphocytes

Purification: Purified from ascites via Protein G Chromatography

Clone: OX-2

Isotype: IgG1

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.1 mg/ml

Buffer: FITC conjugated Ig buffered in PBS, 0.02% NaN and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CD200

Target: CD200

Alternative Name: OX-2 (CD200 Products)

Synonyms: MOX1 antibody, MOX2 antibody, MRC antibody, OX-2 antibody, CD200 antibody, Cspmo2 antibody, MRCOX2 antibody, Mox2 antibody, DKFZp459C0716 antibody, OX2 antibody, CD200 molecule antibody, Cd200 molecule antibody, CD200 antigen antibody, CD200 antibody, Cd200 antibody

Background: Mouse anti-rat OX-2 monoclonal antibody recognizes a monomorphic determinant present on rat thymocytes, brain, follicular dendritic cells in lymphoid organs, vascular endothelium, and at low levels on some smooth muscle and B lymphocytes. The purified brain and thymocyte OX-2 antigens are glycoproteins with apparent M.W. of 41 KDa and 47 KDa respectively. The amino acid composition of brain and thymocyte OX-2 antigen are very similar and are antigenically similar to those found on other tissues. The carbohydrate composition shows that this antigen is highly glycosylated (brain OX-2 - 24% and thymocyte OX-2 - 33% carbohydrate by weight). The OX-2 antigen shows similarities to the Thy-1 antigen in its odd pattern of tissue distribution, carbohydrate composition and characteristic migration on SDS- PAGE. Also, the OX-2 antigens, like Thy-1 antigens, have homologies with immunoglobulin domains the overall structure of OX-2 is similar to an Ig light chain or the T cell receptor chain. Because of its distribution, it is thought to play a role in mediating recognition events at cell surfaces. This clone can be used in flow cytometry, affinity chromatography, immunohistochemistry and in binding assays. It is also useful for labeling the follicular dendritic cells thought to be involved in the generation of B cell memory as it does not label the Ia-positive dendritic cells present in the T-dependant areas of lymphoid organs.