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Integrin beta 4 antibody

ITGB4 Reactivity: Mouse WB, IHC, IP Host: Rat Monoclonal 346-11A unconjugated
Catalog No. ABIN135373
  • Target See all Integrin beta 4 (ITGB4) Antibodies
    Integrin beta 4 (ITGB4)
    Reactivity
    • 82
    • 26
    • 25
    • 3
    • 3
    • 1
    Mouse
    Host
    • 57
    • 36
    • 7
    • 2
    Rat
    Clonality
    • 51
    • 51
    Monoclonal
    Conjugate
    • 54
    • 8
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Integrin beta 4 antibody is un-conjugated
    Application
    • 52
    • 42
    • 31
    • 29
    • 19
    • 14
    • 14
    • 13
    • 13
    • 9
    • 8
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
    Characteristics
    The antibody detects: Integrin 4 chain (CD104), Mr 200 kDa
    It is not known if the monoclonal antibody 346-11A can block the adhesion.
    Purification
    Purified
    Immunogen
    Tumor-associated antigen TSP-180 immunoaffinity purified from a transplantable BALB/c mouse lung cell carcinoma.1
    Clone
    346-11A
    Isotype
    IgG2a
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    Discover our top product ITGB4 Primary Antibody
  • Application Notes
    Working Dilution:
    Immunohistochemistry: 1-5 µg/mL
    Representative data are included in this product insert.

    Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
    Sample Volume
    1 mL
    Restrictions
    For Research Use only
  • Buffer
    Product is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.0.
    Preservative
    Azide free
    Handling Advice
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Storage
    4 °C
  • Target
    Integrin beta 4 (ITGB4)
    Alternative Name
    CD104 (ITGB4 Products)
    Synonyms
    AA407042 antibody, C230078O20 antibody, CD104 antibody, integrin subunit beta 4 antibody, integrin beta 4 antibody, ITGB4 antibody, Itgb4 antibody
    Background
    CD104 represents the integrin 4 subunit that associates non-covalently with integrin 6 (CD49f) to form the 64 integrin heterodimer. The 64 complex is expressed on the basal surface of a variety of epithelial cell types, particularly on stratified squamous epithelia. It is also found in peripheral nerves, in certain subsets of endothelial cells, and on immature thymocytes, and has been found to be associated with a number of malignant tissues. Hemidesmosomal 64 plays an important role in the adhesion of epithelial cells to basement membranes via interactions with laminin and/or kalinin anchoring filaments.
    Pathways
    Integrin Complex
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